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3D mouse pose from single-view video and a new dataset
We present a method to infer the 3D pose of mice, including the limbs and feet, from monocular videos. Many human clinical conditions and their corresponding animal models result in abnormal motion, and accurately measuring 3D motion at scale offers insights into health. The 3D poses improve classif...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442417/ https://www.ncbi.nlm.nih.gov/pubmed/37604955 http://dx.doi.org/10.1038/s41598-023-40738-w |
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author | Hu, Bo Seybold, Bryan Yang, Shan Sud, Avneesh Liu, Yi Barron, Karla Cha, Paulyn Cosino, Marcelo Karlsson, Ellie Kite, Janessa Kolumam, Ganesh Preciado, Joseph Zavala-Solorio, José Zhang, Chunlian Zhang, Xiaomeng Voorbach, Martin Tovcimak, Ann E. Ruby, J. Graham Ross, David A. |
author_facet | Hu, Bo Seybold, Bryan Yang, Shan Sud, Avneesh Liu, Yi Barron, Karla Cha, Paulyn Cosino, Marcelo Karlsson, Ellie Kite, Janessa Kolumam, Ganesh Preciado, Joseph Zavala-Solorio, José Zhang, Chunlian Zhang, Xiaomeng Voorbach, Martin Tovcimak, Ann E. Ruby, J. Graham Ross, David A. |
author_sort | Hu, Bo |
collection | PubMed |
description | We present a method to infer the 3D pose of mice, including the limbs and feet, from monocular videos. Many human clinical conditions and their corresponding animal models result in abnormal motion, and accurately measuring 3D motion at scale offers insights into health. The 3D poses improve classification of health-related attributes over 2D representations. The inferred poses are accurate enough to estimate stride length even when the feet are mostly occluded. This method could be applied as part of a continuous monitoring system to non-invasively measure animal health, as demonstrated by its use in successfully classifying animals based on age and genotype. We introduce the Mouse Pose Analysis Dataset, the first large scale video dataset of lab mice in their home cage with ground truth keypoint and behavior labels. The dataset also contains high resolution mouse CT scans, which we use to build the shape models for 3D pose reconstruction. |
format | Online Article Text |
id | pubmed-10442417 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-104424172023-08-23 3D mouse pose from single-view video and a new dataset Hu, Bo Seybold, Bryan Yang, Shan Sud, Avneesh Liu, Yi Barron, Karla Cha, Paulyn Cosino, Marcelo Karlsson, Ellie Kite, Janessa Kolumam, Ganesh Preciado, Joseph Zavala-Solorio, José Zhang, Chunlian Zhang, Xiaomeng Voorbach, Martin Tovcimak, Ann E. Ruby, J. Graham Ross, David A. Sci Rep Article We present a method to infer the 3D pose of mice, including the limbs and feet, from monocular videos. Many human clinical conditions and their corresponding animal models result in abnormal motion, and accurately measuring 3D motion at scale offers insights into health. The 3D poses improve classification of health-related attributes over 2D representations. The inferred poses are accurate enough to estimate stride length even when the feet are mostly occluded. This method could be applied as part of a continuous monitoring system to non-invasively measure animal health, as demonstrated by its use in successfully classifying animals based on age and genotype. We introduce the Mouse Pose Analysis Dataset, the first large scale video dataset of lab mice in their home cage with ground truth keypoint and behavior labels. The dataset also contains high resolution mouse CT scans, which we use to build the shape models for 3D pose reconstruction. Nature Publishing Group UK 2023-08-21 /pmc/articles/PMC10442417/ /pubmed/37604955 http://dx.doi.org/10.1038/s41598-023-40738-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Hu, Bo Seybold, Bryan Yang, Shan Sud, Avneesh Liu, Yi Barron, Karla Cha, Paulyn Cosino, Marcelo Karlsson, Ellie Kite, Janessa Kolumam, Ganesh Preciado, Joseph Zavala-Solorio, José Zhang, Chunlian Zhang, Xiaomeng Voorbach, Martin Tovcimak, Ann E. Ruby, J. Graham Ross, David A. 3D mouse pose from single-view video and a new dataset |
title | 3D mouse pose from single-view video and a new dataset |
title_full | 3D mouse pose from single-view video and a new dataset |
title_fullStr | 3D mouse pose from single-view video and a new dataset |
title_full_unstemmed | 3D mouse pose from single-view video and a new dataset |
title_short | 3D mouse pose from single-view video and a new dataset |
title_sort | 3d mouse pose from single-view video and a new dataset |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442417/ https://www.ncbi.nlm.nih.gov/pubmed/37604955 http://dx.doi.org/10.1038/s41598-023-40738-w |
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