Cargando…

3D mouse pose from single-view video and a new dataset

We present a method to infer the 3D pose of mice, including the limbs and feet, from monocular videos. Many human clinical conditions and their corresponding animal models result in abnormal motion, and accurately measuring 3D motion at scale offers insights into health. The 3D poses improve classif...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Bo, Seybold, Bryan, Yang, Shan, Sud, Avneesh, Liu, Yi, Barron, Karla, Cha, Paulyn, Cosino, Marcelo, Karlsson, Ellie, Kite, Janessa, Kolumam, Ganesh, Preciado, Joseph, Zavala-Solorio, José, Zhang, Chunlian, Zhang, Xiaomeng, Voorbach, Martin, Tovcimak, Ann E., Ruby, J. Graham, Ross, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442417/
https://www.ncbi.nlm.nih.gov/pubmed/37604955
http://dx.doi.org/10.1038/s41598-023-40738-w
_version_ 1785093592868454400
author Hu, Bo
Seybold, Bryan
Yang, Shan
Sud, Avneesh
Liu, Yi
Barron, Karla
Cha, Paulyn
Cosino, Marcelo
Karlsson, Ellie
Kite, Janessa
Kolumam, Ganesh
Preciado, Joseph
Zavala-Solorio, José
Zhang, Chunlian
Zhang, Xiaomeng
Voorbach, Martin
Tovcimak, Ann E.
Ruby, J. Graham
Ross, David A.
author_facet Hu, Bo
Seybold, Bryan
Yang, Shan
Sud, Avneesh
Liu, Yi
Barron, Karla
Cha, Paulyn
Cosino, Marcelo
Karlsson, Ellie
Kite, Janessa
Kolumam, Ganesh
Preciado, Joseph
Zavala-Solorio, José
Zhang, Chunlian
Zhang, Xiaomeng
Voorbach, Martin
Tovcimak, Ann E.
Ruby, J. Graham
Ross, David A.
author_sort Hu, Bo
collection PubMed
description We present a method to infer the 3D pose of mice, including the limbs and feet, from monocular videos. Many human clinical conditions and their corresponding animal models result in abnormal motion, and accurately measuring 3D motion at scale offers insights into health. The 3D poses improve classification of health-related attributes over 2D representations. The inferred poses are accurate enough to estimate stride length even when the feet are mostly occluded. This method could be applied as part of a continuous monitoring system to non-invasively measure animal health, as demonstrated by its use in successfully classifying animals based on age and genotype. We introduce the Mouse Pose Analysis Dataset, the first large scale video dataset of lab mice in their home cage with ground truth keypoint and behavior labels. The dataset also contains high resolution mouse CT scans, which we use to build the shape models for 3D pose reconstruction.
format Online
Article
Text
id pubmed-10442417
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-104424172023-08-23 3D mouse pose from single-view video and a new dataset Hu, Bo Seybold, Bryan Yang, Shan Sud, Avneesh Liu, Yi Barron, Karla Cha, Paulyn Cosino, Marcelo Karlsson, Ellie Kite, Janessa Kolumam, Ganesh Preciado, Joseph Zavala-Solorio, José Zhang, Chunlian Zhang, Xiaomeng Voorbach, Martin Tovcimak, Ann E. Ruby, J. Graham Ross, David A. Sci Rep Article We present a method to infer the 3D pose of mice, including the limbs and feet, from monocular videos. Many human clinical conditions and their corresponding animal models result in abnormal motion, and accurately measuring 3D motion at scale offers insights into health. The 3D poses improve classification of health-related attributes over 2D representations. The inferred poses are accurate enough to estimate stride length even when the feet are mostly occluded. This method could be applied as part of a continuous monitoring system to non-invasively measure animal health, as demonstrated by its use in successfully classifying animals based on age and genotype. We introduce the Mouse Pose Analysis Dataset, the first large scale video dataset of lab mice in their home cage with ground truth keypoint and behavior labels. The dataset also contains high resolution mouse CT scans, which we use to build the shape models for 3D pose reconstruction. Nature Publishing Group UK 2023-08-21 /pmc/articles/PMC10442417/ /pubmed/37604955 http://dx.doi.org/10.1038/s41598-023-40738-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Hu, Bo
Seybold, Bryan
Yang, Shan
Sud, Avneesh
Liu, Yi
Barron, Karla
Cha, Paulyn
Cosino, Marcelo
Karlsson, Ellie
Kite, Janessa
Kolumam, Ganesh
Preciado, Joseph
Zavala-Solorio, José
Zhang, Chunlian
Zhang, Xiaomeng
Voorbach, Martin
Tovcimak, Ann E.
Ruby, J. Graham
Ross, David A.
3D mouse pose from single-view video and a new dataset
title 3D mouse pose from single-view video and a new dataset
title_full 3D mouse pose from single-view video and a new dataset
title_fullStr 3D mouse pose from single-view video and a new dataset
title_full_unstemmed 3D mouse pose from single-view video and a new dataset
title_short 3D mouse pose from single-view video and a new dataset
title_sort 3d mouse pose from single-view video and a new dataset
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442417/
https://www.ncbi.nlm.nih.gov/pubmed/37604955
http://dx.doi.org/10.1038/s41598-023-40738-w
work_keys_str_mv AT hubo 3dmouseposefromsingleviewvideoandanewdataset
AT seyboldbryan 3dmouseposefromsingleviewvideoandanewdataset
AT yangshan 3dmouseposefromsingleviewvideoandanewdataset
AT sudavneesh 3dmouseposefromsingleviewvideoandanewdataset
AT liuyi 3dmouseposefromsingleviewvideoandanewdataset
AT barronkarla 3dmouseposefromsingleviewvideoandanewdataset
AT chapaulyn 3dmouseposefromsingleviewvideoandanewdataset
AT cosinomarcelo 3dmouseposefromsingleviewvideoandanewdataset
AT karlssonellie 3dmouseposefromsingleviewvideoandanewdataset
AT kitejanessa 3dmouseposefromsingleviewvideoandanewdataset
AT kolumamganesh 3dmouseposefromsingleviewvideoandanewdataset
AT preciadojoseph 3dmouseposefromsingleviewvideoandanewdataset
AT zavalasoloriojose 3dmouseposefromsingleviewvideoandanewdataset
AT zhangchunlian 3dmouseposefromsingleviewvideoandanewdataset
AT zhangxiaomeng 3dmouseposefromsingleviewvideoandanewdataset
AT voorbachmartin 3dmouseposefromsingleviewvideoandanewdataset
AT tovcimakanne 3dmouseposefromsingleviewvideoandanewdataset
AT rubyjgraham 3dmouseposefromsingleviewvideoandanewdataset
AT rossdavida 3dmouseposefromsingleviewvideoandanewdataset