Cargando…
TRAIP resolves DNA replication-transcription conflicts during the S-phase of unperturbed cells
Cell division is the basis for the propagation of life and requires accurate duplication of all genetic information. DNA damage created during replication (replication stress) is a major cause of cancer, premature aging and a spectrum of other human disorders. Over the years, TRAIP E3 ubiquitin liga...
Autores principales: | Scaramuzza, Shaun, Jones, Rebecca M., Sadurni, Martina Muste, Reynolds-Winczura, Alicja, Poovathumkadavil, Divyasree, Farrell, Abigail, Natsume, Toyoaki, Rojas, Patricia, Cuesta, Cyntia Fernandez, Kanemaki, Masato T., Saponaro, Marco, Gambus, Agnieszka |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442450/ https://www.ncbi.nlm.nih.gov/pubmed/37604812 http://dx.doi.org/10.1038/s41467-023-40695-y |
Ejemplares similares
-
Mitotic replisome disassembly depends on TRAIP ubiquitin ligase activity
por: Priego Moreno, Sara, et al.
Publicado: (2019) -
Regulation of Unperturbed DNA Replication by Ubiquitylation
por: Priego Moreno, Sara, et al.
Publicado: (2015) -
The p97 segregase cofactor Ubxn7 facilitates replisome disassembly during S-phase
por: Tarcan, Zeynep, et al.
Publicado: (2022) -
DONSON facilitates Cdc45 and GINS chromatin association and is essential for DNA replication initiation
por: Kingsley, Georgia, et al.
Publicado: (2023) -
TRAIP regulates replication fork recovery and progression via PCNA
por: Feng, Wanjuan, et al.
Publicado: (2016)