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Prognostic values of geriatric nutrition risk index on elderly patients after spinal tuberculosis surgery

BACKGROUND: Spinal tuberculosis (STB) is a significant public health concern, especially in elderly patients, due to its chronic and debilitating nature. Nutritional status is a critical factor affecting the prognosis of STB patients. The geriatric nutritional risk index (GNRI) has been established...

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Autores principales: Huang, Yong, Wu, Ruibang, Xia, Qinghong, Liu, Limin, Feng, Ganjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442490/
https://www.ncbi.nlm.nih.gov/pubmed/37614748
http://dx.doi.org/10.3389/fnut.2023.1229427
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author Huang, Yong
Wu, Ruibang
Xia, Qinghong
Liu, Limin
Feng, Ganjun
author_facet Huang, Yong
Wu, Ruibang
Xia, Qinghong
Liu, Limin
Feng, Ganjun
author_sort Huang, Yong
collection PubMed
description BACKGROUND: Spinal tuberculosis (STB) is a significant public health concern, especially in elderly patients, due to its chronic and debilitating nature. Nutritional status is a critical factor affecting the prognosis of STB patients. The geriatric nutritional risk index (GNRI) has been established as a reliable predictor of adverse outcomes in various diseases, but its correlation with surgical outcomes in elderly STB patients has not been studied. OBJECTIVE: The study aimed to assess the prognostic value of the GNRI in elderly patients with STB who underwent surgery. METHODS: We conducted a retrospective analysis of medical records of elderly patients (65 years or older) diagnosed with active STB who underwent surgical treatment. Data collection included patient demographics, comorbidities, clinical history, laboratory testing, and surgical factors. GNRI was calculated using serum albumin levels and body weight. Postoperative complications were observed and recorded. The patients were followed up for at least 1 year, and their clinical cure status was assessed based on predefined criteria. RESULTS: A total of 91 patients were included in the study. We found that a GNRI value of <98.63 g/dL was a cutoff value for predicting unfavorable clinical prognosis in elderly STB patients undergoing surgery. Patients with a low GNRI had higher Charlson Comorbidity Index scores, were more likely to receive red blood cell transfusions, and had a higher prevalence of overall complications, particularly pneumonia. The unfavorable clinical prognosis group had lower GNRI scores compared to the favorable prognosis group. Multivariate analysis showed that lower GNRI independently predicted unfavorable clinical outcomes in elderly STB patients. CONCLUSION: The study concluded that the GNRI is a valuable biomarker for predicting prognosis in elderly STB patients undergoing surgical intervention. Patients with lower GNRI scores had worse outcomes and a higher incidence of complications.
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spelling pubmed-104424902023-08-23 Prognostic values of geriatric nutrition risk index on elderly patients after spinal tuberculosis surgery Huang, Yong Wu, Ruibang Xia, Qinghong Liu, Limin Feng, Ganjun Front Nutr Nutrition BACKGROUND: Spinal tuberculosis (STB) is a significant public health concern, especially in elderly patients, due to its chronic and debilitating nature. Nutritional status is a critical factor affecting the prognosis of STB patients. The geriatric nutritional risk index (GNRI) has been established as a reliable predictor of adverse outcomes in various diseases, but its correlation with surgical outcomes in elderly STB patients has not been studied. OBJECTIVE: The study aimed to assess the prognostic value of the GNRI in elderly patients with STB who underwent surgery. METHODS: We conducted a retrospective analysis of medical records of elderly patients (65 years or older) diagnosed with active STB who underwent surgical treatment. Data collection included patient demographics, comorbidities, clinical history, laboratory testing, and surgical factors. GNRI was calculated using serum albumin levels and body weight. Postoperative complications were observed and recorded. The patients were followed up for at least 1 year, and their clinical cure status was assessed based on predefined criteria. RESULTS: A total of 91 patients were included in the study. We found that a GNRI value of <98.63 g/dL was a cutoff value for predicting unfavorable clinical prognosis in elderly STB patients undergoing surgery. Patients with a low GNRI had higher Charlson Comorbidity Index scores, were more likely to receive red blood cell transfusions, and had a higher prevalence of overall complications, particularly pneumonia. The unfavorable clinical prognosis group had lower GNRI scores compared to the favorable prognosis group. Multivariate analysis showed that lower GNRI independently predicted unfavorable clinical outcomes in elderly STB patients. CONCLUSION: The study concluded that the GNRI is a valuable biomarker for predicting prognosis in elderly STB patients undergoing surgical intervention. Patients with lower GNRI scores had worse outcomes and a higher incidence of complications. Frontiers Media S.A. 2023-08-08 /pmc/articles/PMC10442490/ /pubmed/37614748 http://dx.doi.org/10.3389/fnut.2023.1229427 Text en Copyright © 2023 Huang, Wu, Xia, Liu and Feng. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Huang, Yong
Wu, Ruibang
Xia, Qinghong
Liu, Limin
Feng, Ganjun
Prognostic values of geriatric nutrition risk index on elderly patients after spinal tuberculosis surgery
title Prognostic values of geriatric nutrition risk index on elderly patients after spinal tuberculosis surgery
title_full Prognostic values of geriatric nutrition risk index on elderly patients after spinal tuberculosis surgery
title_fullStr Prognostic values of geriatric nutrition risk index on elderly patients after spinal tuberculosis surgery
title_full_unstemmed Prognostic values of geriatric nutrition risk index on elderly patients after spinal tuberculosis surgery
title_short Prognostic values of geriatric nutrition risk index on elderly patients after spinal tuberculosis surgery
title_sort prognostic values of geriatric nutrition risk index on elderly patients after spinal tuberculosis surgery
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442490/
https://www.ncbi.nlm.nih.gov/pubmed/37614748
http://dx.doi.org/10.3389/fnut.2023.1229427
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