Cargando…

Current status and prospects of GREM1 research in cancer (Review)

GREM1 is a secreted protein that antagonizes bone morphogenetic proteins (BMPs) and participates in critical biological processes, including embryonic development, organogenesis and tissue differentiation. Gremlin 1 (GREM1) is also an inhibitor of TGF-β and a ligand for vascular endothelial growth f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Dantong, Zhao, Dong, Wang, Naixue, Cai, Fei, Jiang, Mingzhe, Zheng, Zhendong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442762/ https://www.ncbi.nlm.nih.gov/pubmed/37614374 http://dx.doi.org/10.3892/mco.2023.2665

Ejemplares similares

Current Situation and Prospect of Adoptive Cellular Immunotherapy for Malignancies
por: Zhao, Dong, et al.
Publicado: (2023)

GREM1 is a potential biomarker for the progression and prognosis of bladder cancer
por: Jiang, Peng-cheng, et al.
Publicado: (2023)

BMP signalling in human fetal ovary somatic cells is modulated in a gene-specific fashion by GREM1 and GREM2
por: Bayne, Rosemary A., et al.
Publicado: (2016)

GREM 1 and POLE variants in hereditary colorectal cancer syndromes
por: Rohlin, Anna, et al.
Publicado: (2015)

GREM1 is expressed in the cancer-associated myofibroblasts of basal cell carcinomas
por: Kim, Hye Sung, et al.
Publicado: (2017)

GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients
por: Neckmann, Ulrike, et al.
Publicado: (2019)

Allelic Depletion of grem1 Attenuates Diabetic Kidney Disease
por: Roxburgh, Sarah A., et al.
Publicado: (2009)

GREM2 is associated with human central obesity and inhibits visceral preadipocyte browning
por: Liu, Wen, et al.
Publicado: (2022)

Loss of Grem1-articular cartilage progenitor cells causes osteoarthritis
por: Ng, Jia Q., et al.
Publicado: (2023)

Nicotine exacerbates diabetic nephropathy through upregulation of Grem1 expression
por: Chen, Jianning, et al.
Publicado: (2023)

Loss of Grem1-lineage chondrogenic progenitor cells causes osteoarthritis
por: Ng, Jia Q., et al.
Publicado: (2023)

MiR-103a-3p Contributes to the Progression of Colorectal Cancer by Regulating GREM2 Expression
por: Zhang, Zongxiang, et al.
Publicado: (2022)

Wattles in goats are associated with the FMN1/GREM1 region on chromosome 10
por: Reber, I., et al.
Publicado: (2015)

Butyrate and obesity: Current research status and future prospect
por: Peng, Ke, et al.
Publicado: (2023)

Increased hypospadias risk by GREM1 rs3743104[G] in the southern Han Chinese population
por: Deng, Fuming, et al.
Publicado: (2021)

GREM, a technique for genome-wide isolation and quantitative analysis of promoter active repeats
por: Buzdin, Anton, et al.
Publicado: (2006)

Cell fusion in cancer hallmarks: Current research status and future indications
por: Wang, Hao-Fei, et al.
Publicado: (2021)

NPLOC4 is a potential target and a poor prognostic signature in lung squamous cell carcinoma
por: Wang, Naixue, et al.
Publicado: (2023)

Knockdown of circRNA_0007534 suppresses the tumorigenesis of cervical cancer via miR-206/GREM1 axis
por: Sun, Qiang, et al.
Publicado: (2021)

TCF7L2, CASC8, and GREM1 polymorphism and colorectal cancer in south-eastern Romanian population
por: Mitroi, Anca Florentina, et al.
Publicado: (2023)

Grem1 accelerates nucleus pulposus cell apoptosis and intervertebral disc degeneration by inhibiting TGF-β-mediated Smad2/3 phosphorylation
por: Chen, Shunlun, et al.
Publicado: (2022)

Bone Morphogenetic Protein Pathway Antagonism by Grem1 Regulates Epithelial Cell Fate in Intestinal Regeneration
por: Koppens, Martijn A. J., et al.
Publicado: (2021)

GREM1 is a novel serum diagnostic marker and potential therapeutic target for pancreatic ductal adenocarcinoma
por: Yang, Sen, et al.
Publicado: (2022)

GREM1/PPP2R3A expression in heterogeneous fibroblasts initiates pulmonary fibrosis
por: Shi, Xiaoni, et al.
Publicado: (2022)

A functional variant in GREM1 confers risk for colorectal cancer by disrupting a hsa-miR-185-3p binding site
por: Li, Jiaoyuan, et al.
Publicado: (2017)

SNPs associated with colorectal cancer at 15q13.3 affect risk enhancers that modulate GREM1 gene expression
por: Fortini, Barbara K., et al.
Publicado: (2021)

Highlights on molecular targets for radiosensitization of breast cancer cells: Current research status and prospects
por: Zhou, Zhi‐Rui, et al.
Publicado: (2018)

GREM1, FRZB and DKK1 mRNA levels correlate with osteoarthritis and are regulated by osteoarthritis-associated factors
por: Leijten, Jeroen CH, et al.
Publicado: (2013)

Association of TCF7L2, CASC8 and GREM1 Polymorphisms in Patients with Colorectal Cancer and Type II Diabetes Mellitus
por: Mitroi, Anca Florentina, et al.
Publicado: (2022)

Retraction Note: Knockdown of circRNA_0007534 suppresses the tumorigenesis of cervical cancer via miR-206/GREM1 axis
por: Sun, Qiang, et al.
Publicado: (2022)

A Genetic Locus within the FMN1/GREM1 Gene Region Interacts with Body Mass Index in Colorectal Cancer Risk
por: Aglago, Elom K., et al.
Publicado: (2023)

Microbial Risks Caused by Livestock Excrement: Current Research Status and Prospects
por: Abdugheni, Rashidin, et al.
Publicado: (2023)

Predictive Biomarkers for Immunotherapy in Gastric Cancer: Current Status and Emerging Prospects
por: Hou, Wanting, et al.
Publicado: (2023)

miR-27a attenuates adipogenesis and promotes osteogenesis in steroid-induced rat BMSCs by targeting PPARγ and GREM1
por: Gu, Chenxi, et al.
Publicado: (2016)

Current status and patent prospective of animal models in diabetic research
por: Dhuria, Radhey S., et al.
Publicado: (2015)

Current Status and Prospects of Research on Ischemia-Reperfusion Injury and Ferroptosis
por: Hou, Lin, et al.
Publicado: (2022)

Immunotherapy for nasopharyngeal carcinoma: Current status and prospects (Review)
por: Huang, Huageng, et al.
Publicado: (2023)

Overexpression of GREM1 Improves the Survival Capacity of Aged Cardiac Mesenchymal Progenitor Cells via Upregulation of the ERK/NRF2-Associated Antioxidant Signal Pathway
por: Kaur, Gurleen, et al.
Publicado: (2023)

Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside of the crypt base stem cell niche
por: Davis, Hayley, et al.
Publicado: (2014)

SPDR-5 ESTABLISHMENT OF A CONTINUOUS CULTURE METHOD FOR MENINGIOMAS AND THE EFFECTS OF THE GREM2-BMP SIGNALLING PATHWAY ON PROLIFERATION AND ANGIOGENESIS
por: Yokogami, Kiyotaka, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_q0m7bfsandttbk1kui2732crgu