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Dexamethasone attenuates interferon-related cytokine hyperresponsiveness in COVID-19 patients

BACKGROUND: Dexamethasone improves the survival of COVID-19 patients in need of supplemental oxygen therapy. Although its broad immunosuppressive effects are well-described, the immunological mechanisms modulated by dexamethasone in patients hospitalized with COVID-19 remain to be elucidated. OBJECT...

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Detalles Bibliográficos
Autores principales: Engel, Job J., van der Made, Caspar I., Keur, Nick, Setiabudiawan, Todia, Röring, Rutger J., Damoraki, Georgia, Dijkstra, Helga, Lemmers, Heidi, Ioannou, Sofia, Poulakou, Garyfallia, van der Meer, Jos W. M., Giamarellos-Bourboulis, Evangelos J., Kumar, Vinod, van de Veerdonk, Frank L., Netea, Mihai G., Ziogas, Athanasios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442808/
https://www.ncbi.nlm.nih.gov/pubmed/37614228
http://dx.doi.org/10.3389/fimmu.2023.1233318

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