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Site-Specific Glycation of Human Heat Shock Protein (Hsp27) Enhances Its Chaperone Activity

[Image: see text] Non-enzymatic posttranslational modifications are believed to affect at least 30% of human proteins, commonly termed glycation. Many of these modifications are implicated in various pathological conditions, e.g., cataract, diabetes, neurodegenerative diseases, and cancer. Chemical...

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Detalles Bibliográficos
Autores principales: Mukherjee, Somnath, Vogl, Dominik P., Becker, Christian F. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442856/
https://www.ncbi.nlm.nih.gov/pubmed/37449780
http://dx.doi.org/10.1021/acschembio.3c00214