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Site-Specific Glycation of Human Heat Shock Protein (Hsp27) Enhances Its Chaperone Activity
[Image: see text] Non-enzymatic posttranslational modifications are believed to affect at least 30% of human proteins, commonly termed glycation. Many of these modifications are implicated in various pathological conditions, e.g., cataract, diabetes, neurodegenerative diseases, and cancer. Chemical...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442856/ https://www.ncbi.nlm.nih.gov/pubmed/37449780 http://dx.doi.org/10.1021/acschembio.3c00214 |