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Predicting nucleosome positioning using statistical equilibrium models in budding yeast
We present a protocol using thermodynamic models to predict nucleosome positioning with transcription factors (TFs) and chromatin remodelers. We describe step-by-step approaches to annotate genome-wide nucleosome-depleted regions (NDRs), compute nucleosome and TF occupancy, optimize parameters, and...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442889/ https://www.ncbi.nlm.nih.gov/pubmed/36520634 http://dx.doi.org/10.1016/j.xpro.2022.101926 |