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Predicting nucleosome positioning using statistical equilibrium models in budding yeast

We present a protocol using thermodynamic models to predict nucleosome positioning with transcription factors (TFs) and chromatin remodelers. We describe step-by-step approaches to annotate genome-wide nucleosome-depleted regions (NDRs), compute nucleosome and TF occupancy, optimize parameters, and...

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Detalles Bibliográficos
Autores principales: Kharerin, Hungyo, Bai, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442889/
https://www.ncbi.nlm.nih.gov/pubmed/36520634
http://dx.doi.org/10.1016/j.xpro.2022.101926