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Production and N-glycan engineering of Varlilumab in Nicotiana benthamiana

N-glycan engineering has dramatically evolved for the development and quality control of recombinant antibodies. Fc region of IgG contains two N-glycans whose galactose terminals on Fc-glycan have been shown to increase the stability of CH2 domain and improve effector functions. Nicotiana benthamian...

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Detalles Bibliográficos
Autores principales:	Nguyen, Kim Dua, Kajiura, Hiroyuki, Kamiya, Ryo, Yoshida, Takahiro, Misaki, Ryo, Fujiyama, Kazuhito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Plant Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442953/ https://www.ncbi.nlm.nih.gov/pubmed/37615027 http://dx.doi.org/10.3389/fpls.2023.1215580

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