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How to Treat EGFR-Mutated Non–Small Cell Lung Cancer
• Mutations in the EGFR gene are observed in about 15% of NSCLC adenocarcinomas in the United States and are not associated with smoking. There are numerous EGFR mutations, with the most common being exon 19 deletions and the point mutation L858R in exon 21. • Osimertinib, an oral TKI, is used as th...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443111/ https://www.ncbi.nlm.nih.gov/pubmed/37614580 http://dx.doi.org/10.1016/j.jaccao.2023.04.005 |