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Psychiatric Symptoms in Acute and Persisting Forms of COVID-19 Associated with Neural Autoantibodies

(1) Background: In this narrative review, we focus on neural autoantibodies in patients with coronavirus disease 2019 (COVID-19) as a consequence of severe acute respiratory syndrome coronavirus type 2 infection and persisting symptoms of post-COVID-19 syndrome with a psychiatric presentation. (2) M...

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Autor principal: Hansen, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443296/
https://www.ncbi.nlm.nih.gov/pubmed/37606433
http://dx.doi.org/10.3390/antib12030049
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author Hansen, Niels
author_facet Hansen, Niels
author_sort Hansen, Niels
collection PubMed
description (1) Background: In this narrative review, we focus on neural autoantibodies in patients with coronavirus disease 2019 (COVID-19) as a consequence of severe acute respiratory syndrome coronavirus type 2 infection and persisting symptoms of post-COVID-19 syndrome with a psychiatric presentation. (2) Methods: Our methods include using the PubMed database to search for appropriate articles. (3) Results: We first describe the phenomenon of the psychiatric manifestation of COVID-19 in acute and persistent forms, associated with neural autoantibodies, often attributable to encephalopathy or encephalitis. We discuss the spectrum of neural autoantibodies in neuropsychiatric patients affected by COVID-19 and post-COVID-19 syndrome. Evidence from our research suggests that it is highly likely that neural autoantibody production is facilitated by SARS-CoV-2 infection, and that more neuropsychiatric patients than control subjects will present neural autoantibodies. (4) Conclusions: These observations support the hypothesis that acute and persisting forms of COVID-19 promote autoimmune diseases. Our patients therefore require comprehensive evaluation to avoid overlooking such autoantibody-associated psychiatric disorders associated with COVID-19.
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spelling pubmed-104432962023-08-23 Psychiatric Symptoms in Acute and Persisting Forms of COVID-19 Associated with Neural Autoantibodies Hansen, Niels Antibodies (Basel) Review (1) Background: In this narrative review, we focus on neural autoantibodies in patients with coronavirus disease 2019 (COVID-19) as a consequence of severe acute respiratory syndrome coronavirus type 2 infection and persisting symptoms of post-COVID-19 syndrome with a psychiatric presentation. (2) Methods: Our methods include using the PubMed database to search for appropriate articles. (3) Results: We first describe the phenomenon of the psychiatric manifestation of COVID-19 in acute and persistent forms, associated with neural autoantibodies, often attributable to encephalopathy or encephalitis. We discuss the spectrum of neural autoantibodies in neuropsychiatric patients affected by COVID-19 and post-COVID-19 syndrome. Evidence from our research suggests that it is highly likely that neural autoantibody production is facilitated by SARS-CoV-2 infection, and that more neuropsychiatric patients than control subjects will present neural autoantibodies. (4) Conclusions: These observations support the hypothesis that acute and persisting forms of COVID-19 promote autoimmune diseases. Our patients therefore require comprehensive evaluation to avoid overlooking such autoantibody-associated psychiatric disorders associated with COVID-19. MDPI 2023-07-27 /pmc/articles/PMC10443296/ /pubmed/37606433 http://dx.doi.org/10.3390/antib12030049 Text en © 2023 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Hansen, Niels
Psychiatric Symptoms in Acute and Persisting Forms of COVID-19 Associated with Neural Autoantibodies
title Psychiatric Symptoms in Acute and Persisting Forms of COVID-19 Associated with Neural Autoantibodies
title_full Psychiatric Symptoms in Acute and Persisting Forms of COVID-19 Associated with Neural Autoantibodies
title_fullStr Psychiatric Symptoms in Acute and Persisting Forms of COVID-19 Associated with Neural Autoantibodies
title_full_unstemmed Psychiatric Symptoms in Acute and Persisting Forms of COVID-19 Associated with Neural Autoantibodies
title_short Psychiatric Symptoms in Acute and Persisting Forms of COVID-19 Associated with Neural Autoantibodies
title_sort psychiatric symptoms in acute and persisting forms of covid-19 associated with neural autoantibodies
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443296/
https://www.ncbi.nlm.nih.gov/pubmed/37606433
http://dx.doi.org/10.3390/antib12030049
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