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Matrix-Binding, N-Cadherin–Targeting Chimeric Peptide Inhibits Intimal Thickening but Not Endothelial Repair in Balloon-Injured Carotid Arteries

BACKGROUND: Treatment of occluded vessels can involve angioplasty, stenting, and bypass grafting, which can be limited by restenosis and thrombosis. Drug-eluting stents attenuate restenosis, but the current drugs used are cytotoxic, causing smooth muscle cell (SMC) and endothelial cell (EC) death th...

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Detalles Bibliográficos
Autores principales: Burke-Kleinman, Jonah, Rubianto, Jonathan, Hou, Guangpei, Santerre, J. Paul, Bendeck, Michelle P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443629/
https://www.ncbi.nlm.nih.gov/pubmed/37409527
http://dx.doi.org/10.1161/ATVBAHA.123.319400