Antagonistic Roles of Human Platelet Integrin αIIbβ3 and Chemokines in Regulating Neutrophil Activation and Fate on Arterial Thrombi Under Flow

BACKGROUND: Platelets and neutrophils are the first blood cells accumulating at sites of arterial thrombus formation, and both cell types contribute to the pathology of thrombotic events. We aimed to identify key interaction mechanisms between these cells using microfluidic approaches. METHODS: Whol...

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Detalles Bibliográficos
Autores principales: Schönichen, Claudia, Montague, Samantha J., Brouns, Sanne L.N., Burston, James J., Cosemans, Judith M.E.M., Jurk, Kerstin, Kehrel, Beate E., Koenen, Rory R., Ní Áinle, Fionnuala, O’Donnell, Valerie B., Soehnlein, Oliver, Watson, Steve P., Kuijpers, Marijke J.E., Heemskerk, Johan W.M., Nagy, Magdolna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443630/
https://www.ncbi.nlm.nih.gov/pubmed/37409530
http://dx.doi.org/10.1161/ATVBAHA.122.318767

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