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The effect of mutation on neurotoxicity reduction of new chimeric reteplase, a computational study

BACKGROUND AND PURPOSE: Excitotoxicity in nerve cells is a type of neurotoxicity in which excessive stimulation of receptors (such as N-methyl-d-aspartate glutamate receptors (NMDAR)) leads to the influx of high-level calcium ions into cells and finally cell damage or death. This complication can oc...

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Detalles Bibliográficos
Autores principales: pour, Pardis Mohammadi, Mahnam, Karim, Taherzadeh, Mahsa, Ahangarzadeh, Shahrzad, Alibakhshi, Abbas, Mohammadi, Elmira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443662/
https://www.ncbi.nlm.nih.gov/pubmed/37614611
http://dx.doi.org/10.4103/1735-5362.378087