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The effect of mutation on neurotoxicity reduction of new chimeric reteplase, a computational study
BACKGROUND AND PURPOSE: Excitotoxicity in nerve cells is a type of neurotoxicity in which excessive stimulation of receptors (such as N-methyl-d-aspartate glutamate receptors (NMDAR)) leads to the influx of high-level calcium ions into cells and finally cell damage or death. This complication can oc...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443662/ https://www.ncbi.nlm.nih.gov/pubmed/37614611 http://dx.doi.org/10.4103/1735-5362.378087 |