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Photoimmunotherapy retains its anti-tumor efficacy with increasing stromal content in heterotypic pancreatic cancer spheroids

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease characterized by increased levels of desmoplasia that contributes to reduced drug delivery and poor treatment outcomes. In PDAC, the stromal content can account for up to 90% of the total tumor volume. The complex interplay between str...

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Detalles Bibliográficos
Autores principales: Saad, Mohammad A., Zhung, Wonho, Stanley, Margaret Elizabeth, Formica, Sydney, Grimaldo-Garcia, Stacey, Obaid, Girgis, Hasan, Tayyaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443673/
https://www.ncbi.nlm.nih.gov/pubmed/35583476
http://dx.doi.org/10.1021/acs.molpharmaceut.2c00260