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Photoimmunotherapy retains its anti-tumor efficacy with increasing stromal content in heterotypic pancreatic cancer spheroids
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease characterized by increased levels of desmoplasia that contributes to reduced drug delivery and poor treatment outcomes. In PDAC, the stromal content can account for up to 90% of the total tumor volume. The complex interplay between str...
Autores principales: | Saad, Mohammad A., Zhung, Wonho, Stanley, Margaret Elizabeth, Formica, Sydney, Grimaldo-Garcia, Stacey, Obaid, Girgis, Hasan, Tayyaba |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443673/ https://www.ncbi.nlm.nih.gov/pubmed/35583476 http://dx.doi.org/10.1021/acs.molpharmaceut.2c00260 |
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