Influenza A–induced cystic fibrosis transmembrane conductance regulator dysfunction increases susceptibility to Streptococcus pneumoniae

Influenza A virus (IAV) infection is commonly complicated by secondary bacterial infections that lead to increased morbidity and mortality. Our recent work demonstrates that IAV disrupts airway homeostasis, leading to airway pathophysiology resembling cystic fibrosis disease through diminished cysti...

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Detalles Bibliográficos
Autores principales: Earnhardt, Erin Y., Tipper, Jennifer L., D’Mello, Adonis, Jian, Ming-Yuan, Conway, Elijah S., Mobley, James A., Orihuela, Carlos J., Tettelin, Hervé, Harrod, Kevin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443798/
https://www.ncbi.nlm.nih.gov/pubmed/37318849
http://dx.doi.org/10.1172/jci.insight.170022

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