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Alveolar repair following LPS-induced injury requires cell-ECM interactions

During alveolar repair, alveolar type 2 (AT2) epithelial cell progenitors rapidly proliferate and differentiate into flat AT1 epithelial cells. Failure of normal alveolar repair mechanisms can lead to loss of alveolar structure (emphysema) or development of fibrosis, depending on the type and severi...

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Detalles Bibliográficos
Autores principales: Sucre, Jennifer M.S., Bock, Fabian, Negretti, Nicholas M., Benjamin, John T., Gulleman, Peter M., Dong, Xinyu, Ferguson, Kimberly T., Jetter, Christopher S., Han, Wei, Liu, Yang, Kook, Seunghyi, Gokey, Jason J., Guttentag, Susan H., Kropski, Jonathan A., Blackwell, Timothy S., Zent, Roy, Plosa, Erin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443799/
https://www.ncbi.nlm.nih.gov/pubmed/37279065
http://dx.doi.org/10.1172/jci.insight.167211

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