Endothelial-derived FABP4 constitutes the majority of basal circulating hormone and regulates lipolysis-driven insulin secretion

Fatty acid binding protein 4 (FABP4) is a lipid chaperone secreted from adipocytes upon stimulation of lipolysis. Circulating FABP4 levels strongly correlate with obesity and metabolic pathologies in experimental models and humans. While adipocytes have been presumed to be the major source of hormon...

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Detalles Bibliográficos
Autores principales: Inouye, Karen E., Prentice, Kacey J., Lee, Alexandra, Wang, Zeqiu B., Dominguez-Gonzalez, Carla, Chen, Mu Xian, Riveros, Jillian K., Burak, M. Furkan, Lee, Grace Y., Hotamışlıgil, Gökhan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443803/
https://www.ncbi.nlm.nih.gov/pubmed/37279064
http://dx.doi.org/10.1172/jci.insight.164642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443803/
https://www.ncbi.nlm.nih.gov/pubmed/37279064
http://dx.doi.org/10.1172/jci.insight.164642

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