Cargando…

Xiaojianzhong decoction attenuates aspirin-induced gastric mucosal injury via the PI3K/AKT/mTOR/ULK1 and AMPK/ULK1 pathways

CONTEXT: Xiaojianzhong decoction (XJZD), classically prescribed in Chinese medicine, has protective and healing effects on gastric mucosal injury. However, the exact mechanism behind this effect remains unclear. OBJECTIVE: To investigate the effect of XJZD on gastric mucosal injury and explore its u...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Ting, Bao, Shengchuan, Chen, Juan, Zhang, Jiaxiang, Wei, Hailiang, Hu, Xin, Liang, Yan, Li, Jingtao, Yan, Shuguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443964/ https://www.ncbi.nlm.nih.gov/pubmed/37602379 http://dx.doi.org/10.1080/13880209.2023.2243998

Ejemplares similares

Berberine induces autophagy in glioblastoma by targeting the AMPK/mTOR/ULK1-pathway
por: Wang, Jiwei, et al.
Publicado: (2016)

Autophagy regulates the degeneration of the auditory cortex through the AMPK-mTOR-ULK1 signaling pathway
por: Yuan, Jie, et al.
Publicado: (2018)

AMPK/Ulk1-dependent autophagy as a key mTOR regulator in the context of cell pluripotency
por: Suvorova, Irina I., et al.
Publicado: (2019)

The Association of AMPK with ULK1 Regulates Autophagy
por: Lee, Jong Woo, et al.
Publicado: (2010)

Xiaojianzhong decoction prevents gastric precancerous lesions in rats by inhibiting autophagy and glycolysis in gastric mucosal cells
por: Zhang, Jia-Xiang, et al.
Publicado: (2023)

AMPK/mTOR/ULK1 Axis-Mediated Pathway Participates in Apoptosis and Autophagy Induction by Oridonin in Colon Cancer DLD-1 Cells
por: Bu, Heqi, et al.
Publicado: (2020)

Berberine Attenuates IL-1β-Induced Damage of Nucleus Pulposus Cells via Activating the AMPK/mTOR/Ulk1 Pathway
por: Huang, Liaoyuan, et al.
Publicado: (2022)

Apelin-13 Protects Dopaminergic Neurons against Rotenone—Induced Neurotoxicity through the AMPK/mTOR/ULK-1 Mediated Autophagy Activation
por: Chen, Peng, et al.
Publicado: (2020)

Betulinic acid induces autophagy-dependent apoptosis via Bmi-1/ROS/AMPK-mTOR-ULK1 axis in human bladder cancer cells
por: Zhang, Yan, et al.
Publicado: (2021)

PRIMA-1(met) induces autophagy in colorectal cancer cells through upregulation of the mTOR/AMPK-ULK1-Vps34 signaling cascade
por: Li, Xiao-Lan, et al.
Publicado: (2021)

Icariin alleviates osteoarthritis through PI3K/Akt/mTOR/ULK1 signaling pathway
por: Chen, Yan, et al.
Publicado: (2022)

The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs
por: Dite, Toby A., et al.
Publicado: (2017)

Icariin improves brain function decline in aging rats by enhancing neuronal autophagy through the AMPK/mTOR/ULK1 pathway
por: Zheng, Jie, et al.
Publicado: (2021)

SPAG6 silencing induces autophagic cell death in SKM-1 cells via the AMPK/mTOR/ULK1 signaling pathway
por: Zhang, Meng, et al.
Publicado: (2020)

Deciphering the Mechanism of Bushen Huoxue Decotion on Decidualization by Intervening Autophagy via AMPK/mTOR/ULK1: A Novel Discovery for URSA Treatment
por: Zhao, Xiaoxuan, et al.
Publicado: (2022)

Rapamycin Upregulates Autophagy by Inhibiting the mTOR-ULK1 Pathway, Resulting in Reduced Podocyte Injury
por: Wu, Lingling, et al.
Publicado: (2013)

Tangshen Decoction Enhances Podocytes Autophagy to Relieve Diabetic Nephropathy through Modulation of p-AMPK/p-ULK1 Signaling
por: Yan, Ling, et al.
Publicado: (2022)

Puerarin protects rat brain against ischemia/reperfusion injury by suppressing autophagy via the AMPK-mTOR-ULK1 signaling pathway
por: Wang, Jin-Feng, et al.
Publicado: (2018)

AMPK-mTOR-ULK1-mediated autophagy protects carbon tetrachloride-induced acute hepatic failure by inhibiting p21 in rats
por: Wang, Qiwen, et al.
Publicado: (2021)

Antioxidant Compound, Oxyresveratrol, Inhibits APP Production through the AMPK/ULK1/mTOR-Mediated Autophagy Pathway in Mouse Cortical Astrocytes
por: Rahman, Md. Ataur, et al.
Publicado: (2021)

The ingenious ULKs: expanding the repertoire of the ULK complex with phosphoproteomics
por: Mercer, Thomas J., et al.
Publicado: (2021)

The mTOR/ULK1 signaling pathway mediates the autophagy-promoting and osteogenic effects of dicalcium silicate nanoparticles
por: Ruolan, Wang, et al.
Publicado: (2020)

Shabyar Ameliorates High Glucose Induced Retinal Pigment Epithelium Injury Through Suppressing Aldose Reductase and AMPK/mTOR/ULK1 Autophagy Pathway
por: Liu, Xiao Yan, et al.
Publicado: (2022)

Pharmacological Inhibition of ULK1 Kinase Blocks Mammalian Target of Rapamycin (mTOR)-dependent Autophagy
por: Petherick, Katy J., et al.
Publicado: (2015)

The incredible ULKs
por: Alers, Sebastian, et al.
Publicado: (2012)

Late Exercise Preconditioning Promotes Autophagy against Exhaustive Exercise-Induced Myocardial Injury through the Activation of the AMPK-mTOR-ULK1 Pathway
por: Liu, Hong-Tao, et al.
Publicado: (2019)

Guanylate-Binding protein 2b regulates the AMPK/mTOR/ULK1 signalling pathway to induce autophagy during Mycobacterium bovis infection
por: Yu, Youli, et al.
Publicado: (2022)

Ulk1, Not Ulk2, Is Required for Exercise Training-Induced Improvement of Insulin Response in Skeletal Muscle
por: Drake, Joshua C., et al.
Publicado: (2021)

TNFAIP8 regulates gastric cancer growth via mTOR‐Akt‐ULK1 pathway and autophagy signals
por: Chen, Zheng, et al.
Publicado: (2021)

Aurora-B knockdown inhibits osteosarcoma metastasis by inducing autophagy via the mTOR/ULK1 pathway
por: Wu, Xin, et al.
Publicado: (2020)

Echovirus induces autophagy to promote viral replication via regulating mTOR/ULK1 signaling pathway
por: Wu, Chunchen, et al.
Publicado: (2023)

Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965
por: Ahwazi, Danial, et al.
Publicado: (2021)

Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy
por: Laker, Rhianna C., et al.
Publicado: (2017)

Wuhu Decoction Regulates Dendritic Cell Autophagy in the Treatment of Respiratory Syncytial Virus (RSV)-Induced Mouse Asthma by AMPK/ULK1 Signaling Pathway
por: Chen, Xingyu, et al.
Publicado: (2019)

ER-Targeted Beclin 1 Supports Autophagosome Biogenesis in the Absence of ULK1 and ULK2 Kinases
por: Anwar, Tahira, et al.
Publicado: (2019)

Salidroside attenuates hypoxia-induced pulmonary arterial smooth muscle cell proliferation and apoptosis resistance by upregulating autophagy through the AMPK-mTOR-ULK1 pathway
por: Gui, Di, et al.
Publicado: (2017)

Activating autophagy and ferroptosis of 3‑Chloropropane‑1,2‑diol induces injury of human umbilical vein endothelial cells via AMPK/mTOR/ULK1
por: Yi, Xin, et al.
Publicado: (2023)

A novel danshensu/tetramethypyrazine derivative attenuates oxidative stress-induced autophagy injury via the AMPK-mTOR-Ulk1 signaling pathway in cardiomyocytes
por: Xie, Caipeng, et al.
Publicado: (2021)

Camptothecin Inhibits Neddylation to Activate the Protective Autophagy Through NF-κB/AMPK/mTOR/ULK1 Axis in Human Esophageal Cancer Cells
por: Heng, Yongqing, et al.
Publicado: (2021)

mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition
por: Manzoni, Claudia, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_8kqmalfrql3nbrctjtgvsl2ub6