Influence of Timing of Maternal Pertussis Immunization on the Avidity of Transferred Antibodies in Term and Preterm Neonates

The timing of maternal pertussis vaccination influences the titers of cord-blood anti-pertussis antibodies. Whether it affects their avidity is unknown. We demonstrate in 298 term and 72 preterm neonates that antibody avidity is independent of the timing of maternal vaccination, whether comparing se...

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Detalles Bibliográficos
Autores principales: Sartoretti, Julie, Fontannaz, Paola, Martinez de Tejada, Begoña, Othenin-Girard, Véronique, Chilin, Antonina, Lemaître, Barbara, Blanchard-Rohner, Géraldine, Siegrist, Claire-Anne, Eberhardt, Christiane Sigrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444006/
https://www.ncbi.nlm.nih.gov/pubmed/37073575
http://dx.doi.org/10.1093/cid/ciad227
Descripción
Sumario:The timing of maternal pertussis vaccination influences the titers of cord-blood anti-pertussis antibodies. Whether it affects their avidity is unknown. We demonstrate in 298 term and 72 preterm neonates that antibody avidity is independent of the timing of maternal vaccination, whether comparing second with third trimester or intervals before birth.

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