Ether lipid biosynthesis promotes lifespan extension and enables diverse pro-longevity paradigms in Caenorhabditis elegans

Biguanides, including the world’s most prescribed drug for type 2 diabetes, metformin, not only lower blood sugar, but also promote longevity in preclinical models. Epidemiologic studies in humans parallel these findings, indicating favorable effects of metformin on longevity and on reducing the inc...

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Detalles Bibliográficos
Autores principales: Cedillo, Lucydalila, Ahsan, Fasih M, Li, Sainan, Stuhr, Nicole L, Zhou, Yifei, Zhang, Yuyao, Adedoja, Adebanjo, Murphy, Luke M, Yerevanian, Armen, Emans, Sinclair, Dao, Khoi, Li, Zhaozhi, Peterson, Nicholas D, Watrous, Jeramie, Jain, Mohit, Das, Sudeshna, Pukkila-Worley, Read, Curran, Sean P, Soukas, Alexander A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444025/
https://www.ncbi.nlm.nih.gov/pubmed/37606250
http://dx.doi.org/10.7554/eLife.82210

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