Sulodexide improves vascular permeability via glycocalyx remodelling in endothelial cells during sepsis

BACKGROUND: Degradation of the endothelial glycocalyx is critical for sepsis-associated lung injury and pulmonary vascular permeability. We investigated whether sulodexide, a precursor for the synthesis of glycosaminoglycans, plays a biological role in glycocalyx remodeling and improves endothelial...

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Detalles Bibliográficos
Autores principales: Ying, Jiayun, Zhang, Caiyan, Wang, Yaodong, Liu, Tingyan, Yu, Zhenhao, Wang, Kexin, Chen, Weiming, Zhou, Yufeng, Lu, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444196/
https://www.ncbi.nlm.nih.gov/pubmed/37614234
http://dx.doi.org/10.3389/fimmu.2023.1172892

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