TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation

Oncogene-induced DNA replication stress (RS) and consequent pathogenic R-loop formation are known to impede S phase progression. Nonetheless, cancer cells continuously proliferate under such high-stressed conditions through incompletely understood mechanisms. Here, we report taurine upregulated gene...

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Detalles Bibliográficos
Autores principales: Suzuki, Miho M., Iijima, Kenta, Ogami, Koichi, Shinjo, Keiko, Murofushi, Yoshiteru, Xie, Jingqi, Wang, Xuebing, Kitano, Yotaro, Mamiya, Akira, Kibe, Yuji, Nishimura, Tatsunori, Ohka, Fumiharu, Saito, Ryuta, Sato, Shinya, Kobayashi, Junya, Yao, Ryoji, Miyata, Kanjiro, Kataoka, Kazunori, Suzuki, Hiroshi I., Kondo, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444773/
https://www.ncbi.nlm.nih.gov/pubmed/37607907
http://dx.doi.org/10.1038/s41467-023-40243-8

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