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Cholesterol removal improves performance of a model biomimetic system to co-deliver a photothermal agent and a STING agonist for cancer immunotherapy

Biological membranes often play important functional roles in biomimetic drug delivery systems. We discover that the circulation time and targeting capability of biological membrane coated nanovehicles can be significantly improved by reducing cholesterol level in the coating membrane. A proof-of-co...

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Detalles Bibliográficos
Autores principales: Li, Lin, Zhang, Mengxing, Li, Jing, Liu, Tiantian, Bao, Qixue, Li, Xi, Long, Jiaying, Fu, Leyao, Zhang, Zhirong, Huang, Shiqi, Liu, Zhenmi, Zhang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444796/
https://www.ncbi.nlm.nih.gov/pubmed/37607938
http://dx.doi.org/10.1038/s41467-023-40814-9