Bile acid-dependent transcription factors and chromatin accessibility determine regional heterogeneity of intestinal antimicrobial peptides

Antimicrobial peptides (AMPs) are important mediators of intestinal immune surveillance. However, the regional heterogeneity of AMPs and its regulatory mechanisms remain obscure. Here, we clarified the regional heterogeneity of intestinal AMPs at the single-cell level, and revealed a cross-lineages...

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Detalles Bibliográficos
Autores principales: Wang, Yue, Yu, Yanbo, Li, Lixiang, Zheng, Mengqi, Zhou, Jiawei, Gong, Haifan, Feng, Bingcheng, Wang, Xiao, Meng, Xuanlin, Cui, Yanyan, Xia, Yanan, Chu, Shuzheng, Lin, Lin, Chang, Huijun, Zhou, Ruchen, Ma, Mingjun, Li, Zhen, Ji, Rui, Lu, Ming, Yang, Xiaoyun, Zuo, Xiuli, Li, Shiyang, Li, Yanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444805/
https://www.ncbi.nlm.nih.gov/pubmed/37607912
http://dx.doi.org/10.1038/s41467-023-40565-7

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