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The deubiquitinase Leon/USP5 interacts with Atg1/ULK1 and antagonizes autophagy

Accumulating evidence has shown that the quality of proteins must be tightly monitored and controlled to maintain cellular proteostasis. Misfolded proteins and protein aggregates are targeted for degradation through the ubiquitin proteasome (UPS) and autophagy-lysosome systems. The ubiquitination an...

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Detalles Bibliográficos
Autores principales:	Pai, Yueh-Ling, Lin, Yuchieh Jay, Peng, Wen-Hsin, Huang, Li-Ting, Chou, He-Yen, Wang, Chien-Hsiang, Chien, Cheng-Ting, Chen, Guang-Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444890/ https://www.ncbi.nlm.nih.gov/pubmed/37607937 http://dx.doi.org/10.1038/s41419-023-06062-x

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