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Invasive breast carcinoma of no special type with medullary pattern: A case report at a tertiary facility in Tanzania

KEY CLINICAL MESSAGE: Describes a rare form of invasive breast cancer of no special type. Not a distinct morphological subtype. Characterized by dense lymphoid infiltrate, syncytial growth, pushing borders, and cells with high‐grade nuclei. Clinically aggressive but carries a better prognosis than o...

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Detalles Bibliográficos
Autores principales: Mremi, Alex, Gnanamuttupulle, Marianne, Ntundu, Shilanaiman Hilary, Henke, Oliver, Chilonga, Kondo, Msuya, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444943/
https://www.ncbi.nlm.nih.gov/pubmed/37621722
http://dx.doi.org/10.1002/ccr3.7844
Descripción
Sumario:KEY CLINICAL MESSAGE: Describes a rare form of invasive breast cancer of no special type. Not a distinct morphological subtype. Characterized by dense lymphoid infiltrate, syncytial growth, pushing borders, and cells with high‐grade nuclei. Clinically aggressive but carries a better prognosis than other more frequent invasive breast carcinomas. ABSTRACT: Invasive breast carcinoma of no special type with medullary pattern (BCNST‐MP) is a rare form of breast tumor, accounting for less than 5% of all invasive breast carcinomas. Its diagnosis is based on histologic criteria. Historically, this tumor was known as medullary carcinoma. Poor morphological reproducibility led to re‐classification. Despite having an aggressive biological behavior, these tumors usually carry a better prognosis compared with other more frequent forms of invasive breast carcinomas. Herein, we present a case of BCNST‐MP in a 58‐year‐old African female, successfully treated in our institution through chemo‐radiation, hormonal therapy and surgery.