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Invasive breast carcinoma of no special type with medullary pattern: A case report at a tertiary facility in Tanzania
KEY CLINICAL MESSAGE: Describes a rare form of invasive breast cancer of no special type. Not a distinct morphological subtype. Characterized by dense lymphoid infiltrate, syncytial growth, pushing borders, and cells with high‐grade nuclei. Clinically aggressive but carries a better prognosis than o...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444943/ https://www.ncbi.nlm.nih.gov/pubmed/37621722 http://dx.doi.org/10.1002/ccr3.7844 |
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author | Mremi, Alex Gnanamuttupulle, Marianne Ntundu, Shilanaiman Hilary Henke, Oliver Chilonga, Kondo Msuya, David |
author_facet | Mremi, Alex Gnanamuttupulle, Marianne Ntundu, Shilanaiman Hilary Henke, Oliver Chilonga, Kondo Msuya, David |
author_sort | Mremi, Alex |
collection | PubMed |
description | KEY CLINICAL MESSAGE: Describes a rare form of invasive breast cancer of no special type. Not a distinct morphological subtype. Characterized by dense lymphoid infiltrate, syncytial growth, pushing borders, and cells with high‐grade nuclei. Clinically aggressive but carries a better prognosis than other more frequent invasive breast carcinomas. ABSTRACT: Invasive breast carcinoma of no special type with medullary pattern (BCNST‐MP) is a rare form of breast tumor, accounting for less than 5% of all invasive breast carcinomas. Its diagnosis is based on histologic criteria. Historically, this tumor was known as medullary carcinoma. Poor morphological reproducibility led to re‐classification. Despite having an aggressive biological behavior, these tumors usually carry a better prognosis compared with other more frequent forms of invasive breast carcinomas. Herein, we present a case of BCNST‐MP in a 58‐year‐old African female, successfully treated in our institution through chemo‐radiation, hormonal therapy and surgery. |
format | Online Article Text |
id | pubmed-10444943 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-104449432023-08-24 Invasive breast carcinoma of no special type with medullary pattern: A case report at a tertiary facility in Tanzania Mremi, Alex Gnanamuttupulle, Marianne Ntundu, Shilanaiman Hilary Henke, Oliver Chilonga, Kondo Msuya, David Clin Case Rep Case Report KEY CLINICAL MESSAGE: Describes a rare form of invasive breast cancer of no special type. Not a distinct morphological subtype. Characterized by dense lymphoid infiltrate, syncytial growth, pushing borders, and cells with high‐grade nuclei. Clinically aggressive but carries a better prognosis than other more frequent invasive breast carcinomas. ABSTRACT: Invasive breast carcinoma of no special type with medullary pattern (BCNST‐MP) is a rare form of breast tumor, accounting for less than 5% of all invasive breast carcinomas. Its diagnosis is based on histologic criteria. Historically, this tumor was known as medullary carcinoma. Poor morphological reproducibility led to re‐classification. Despite having an aggressive biological behavior, these tumors usually carry a better prognosis compared with other more frequent forms of invasive breast carcinomas. Herein, we present a case of BCNST‐MP in a 58‐year‐old African female, successfully treated in our institution through chemo‐radiation, hormonal therapy and surgery. John Wiley and Sons Inc. 2023-08-22 /pmc/articles/PMC10444943/ /pubmed/37621722 http://dx.doi.org/10.1002/ccr3.7844 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Case Report Mremi, Alex Gnanamuttupulle, Marianne Ntundu, Shilanaiman Hilary Henke, Oliver Chilonga, Kondo Msuya, David Invasive breast carcinoma of no special type with medullary pattern: A case report at a tertiary facility in Tanzania |
title | Invasive breast carcinoma of no special type with medullary pattern: A case report at a tertiary facility in Tanzania |
title_full | Invasive breast carcinoma of no special type with medullary pattern: A case report at a tertiary facility in Tanzania |
title_fullStr | Invasive breast carcinoma of no special type with medullary pattern: A case report at a tertiary facility in Tanzania |
title_full_unstemmed | Invasive breast carcinoma of no special type with medullary pattern: A case report at a tertiary facility in Tanzania |
title_short | Invasive breast carcinoma of no special type with medullary pattern: A case report at a tertiary facility in Tanzania |
title_sort | invasive breast carcinoma of no special type with medullary pattern: a case report at a tertiary facility in tanzania |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444943/ https://www.ncbi.nlm.nih.gov/pubmed/37621722 http://dx.doi.org/10.1002/ccr3.7844 |
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