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Invasive breast carcinoma of no special type with medullary pattern: A case report at a tertiary facility in Tanzania

KEY CLINICAL MESSAGE: Describes a rare form of invasive breast cancer of no special type. Not a distinct morphological subtype. Characterized by dense lymphoid infiltrate, syncytial growth, pushing borders, and cells with high‐grade nuclei. Clinically aggressive but carries a better prognosis than o...

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Autores principales: Mremi, Alex, Gnanamuttupulle, Marianne, Ntundu, Shilanaiman Hilary, Henke, Oliver, Chilonga, Kondo, Msuya, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444943/
https://www.ncbi.nlm.nih.gov/pubmed/37621722
http://dx.doi.org/10.1002/ccr3.7844
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author Mremi, Alex
Gnanamuttupulle, Marianne
Ntundu, Shilanaiman Hilary
Henke, Oliver
Chilonga, Kondo
Msuya, David
author_facet Mremi, Alex
Gnanamuttupulle, Marianne
Ntundu, Shilanaiman Hilary
Henke, Oliver
Chilonga, Kondo
Msuya, David
author_sort Mremi, Alex
collection PubMed
description KEY CLINICAL MESSAGE: Describes a rare form of invasive breast cancer of no special type. Not a distinct morphological subtype. Characterized by dense lymphoid infiltrate, syncytial growth, pushing borders, and cells with high‐grade nuclei. Clinically aggressive but carries a better prognosis than other more frequent invasive breast carcinomas. ABSTRACT: Invasive breast carcinoma of no special type with medullary pattern (BCNST‐MP) is a rare form of breast tumor, accounting for less than 5% of all invasive breast carcinomas. Its diagnosis is based on histologic criteria. Historically, this tumor was known as medullary carcinoma. Poor morphological reproducibility led to re‐classification. Despite having an aggressive biological behavior, these tumors usually carry a better prognosis compared with other more frequent forms of invasive breast carcinomas. Herein, we present a case of BCNST‐MP in a 58‐year‐old African female, successfully treated in our institution through chemo‐radiation, hormonal therapy and surgery.
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spelling pubmed-104449432023-08-24 Invasive breast carcinoma of no special type with medullary pattern: A case report at a tertiary facility in Tanzania Mremi, Alex Gnanamuttupulle, Marianne Ntundu, Shilanaiman Hilary Henke, Oliver Chilonga, Kondo Msuya, David Clin Case Rep Case Report KEY CLINICAL MESSAGE: Describes a rare form of invasive breast cancer of no special type. Not a distinct morphological subtype. Characterized by dense lymphoid infiltrate, syncytial growth, pushing borders, and cells with high‐grade nuclei. Clinically aggressive but carries a better prognosis than other more frequent invasive breast carcinomas. ABSTRACT: Invasive breast carcinoma of no special type with medullary pattern (BCNST‐MP) is a rare form of breast tumor, accounting for less than 5% of all invasive breast carcinomas. Its diagnosis is based on histologic criteria. Historically, this tumor was known as medullary carcinoma. Poor morphological reproducibility led to re‐classification. Despite having an aggressive biological behavior, these tumors usually carry a better prognosis compared with other more frequent forms of invasive breast carcinomas. Herein, we present a case of BCNST‐MP in a 58‐year‐old African female, successfully treated in our institution through chemo‐radiation, hormonal therapy and surgery. John Wiley and Sons Inc. 2023-08-22 /pmc/articles/PMC10444943/ /pubmed/37621722 http://dx.doi.org/10.1002/ccr3.7844 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Report
Mremi, Alex
Gnanamuttupulle, Marianne
Ntundu, Shilanaiman Hilary
Henke, Oliver
Chilonga, Kondo
Msuya, David
Invasive breast carcinoma of no special type with medullary pattern: A case report at a tertiary facility in Tanzania
title Invasive breast carcinoma of no special type with medullary pattern: A case report at a tertiary facility in Tanzania
title_full Invasive breast carcinoma of no special type with medullary pattern: A case report at a tertiary facility in Tanzania
title_fullStr Invasive breast carcinoma of no special type with medullary pattern: A case report at a tertiary facility in Tanzania
title_full_unstemmed Invasive breast carcinoma of no special type with medullary pattern: A case report at a tertiary facility in Tanzania
title_short Invasive breast carcinoma of no special type with medullary pattern: A case report at a tertiary facility in Tanzania
title_sort invasive breast carcinoma of no special type with medullary pattern: a case report at a tertiary facility in tanzania
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10444943/
https://www.ncbi.nlm.nih.gov/pubmed/37621722
http://dx.doi.org/10.1002/ccr3.7844
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