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Oral Manifestations of Type II Diabetes Mellitus and Comparison of Blood and Salivary Glucose Levels

Background and introduction Diabetes mellitus is a common systemic disease in nearly all countries. Its prevalence has been increasing. Thus, early detection and control of this disorder are urgent tasks. The average blood glucose, salivary glucose, and glycosylated hemoglobin (HbA1c) levels must be...

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Autores principales: Alagiriswamy, Arun Prasath, Nagaraj, Meena Gayathry, Rajaram Mohan, Karthik, Narayanan, Mohan, Karunakaran, Priyadeepalakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445001/
https://www.ncbi.nlm.nih.gov/pubmed/37621821
http://dx.doi.org/10.7759/cureus.42344
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author Alagiriswamy, Arun Prasath
Nagaraj, Meena Gayathry
Rajaram Mohan, Karthik
Narayanan, Mohan
Karunakaran, Priyadeepalakshmi
author_facet Alagiriswamy, Arun Prasath
Nagaraj, Meena Gayathry
Rajaram Mohan, Karthik
Narayanan, Mohan
Karunakaran, Priyadeepalakshmi
author_sort Alagiriswamy, Arun Prasath
collection PubMed
description Background and introduction Diabetes mellitus is a common systemic disease in nearly all countries. Its prevalence has been increasing. Thus, early detection and control of this disorder are urgent tasks. The average blood glucose, salivary glucose, and glycosylated hemoglobin (HbA1c) levels must be estimated. Aim and objective This study aimed to assess oral manifestations of type 2 diabetes mellitus in relation to HbA1c and compare glucose levels in the saliva and blood. Materials and methods This study examined 60 patients with diabetes who were visiting the Department of Oral Medicine and Radiology as well as the Department of Medicine at Vinayaka Mission’s Sankarachariyar Dental College, Salem, Tamil Nadu, India. In all patients, the blood glucose, saliva glucose, and HbA1c levels were estimated. Results and statistical analysis The patients (aged 40-60 years) have type 2 diabetes mellitus; among them, patients aged 56-60 years were predominant. In the Pearson correlation analysis, a positive correlation was obtained in random blood glucose, salivary glucose, and HbA1c levels. The p-value was 0.001**, which indicated significance. Conclusion This study revealed a clear-cut correlation between blood and salivary glucose levels. Thus, salivary glucose levels can very well become a substitute for blood glucose levels. If the estimated salivary glucose level is used in practice to estimate glucose levels in patients with diabetes, the use of any invasive procedures may be avoided.
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spelling pubmed-104450012023-08-24 Oral Manifestations of Type II Diabetes Mellitus and Comparison of Blood and Salivary Glucose Levels Alagiriswamy, Arun Prasath Nagaraj, Meena Gayathry Rajaram Mohan, Karthik Narayanan, Mohan Karunakaran, Priyadeepalakshmi Cureus Dentistry Background and introduction Diabetes mellitus is a common systemic disease in nearly all countries. Its prevalence has been increasing. Thus, early detection and control of this disorder are urgent tasks. The average blood glucose, salivary glucose, and glycosylated hemoglobin (HbA1c) levels must be estimated. Aim and objective This study aimed to assess oral manifestations of type 2 diabetes mellitus in relation to HbA1c and compare glucose levels in the saliva and blood. Materials and methods This study examined 60 patients with diabetes who were visiting the Department of Oral Medicine and Radiology as well as the Department of Medicine at Vinayaka Mission’s Sankarachariyar Dental College, Salem, Tamil Nadu, India. In all patients, the blood glucose, saliva glucose, and HbA1c levels were estimated. Results and statistical analysis The patients (aged 40-60 years) have type 2 diabetes mellitus; among them, patients aged 56-60 years were predominant. In the Pearson correlation analysis, a positive correlation was obtained in random blood glucose, salivary glucose, and HbA1c levels. The p-value was 0.001**, which indicated significance. Conclusion This study revealed a clear-cut correlation between blood and salivary glucose levels. Thus, salivary glucose levels can very well become a substitute for blood glucose levels. If the estimated salivary glucose level is used in practice to estimate glucose levels in patients with diabetes, the use of any invasive procedures may be avoided. Cureus 2023-07-23 /pmc/articles/PMC10445001/ /pubmed/37621821 http://dx.doi.org/10.7759/cureus.42344 Text en Copyright © 2023, Alagiriswamy et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dentistry
Alagiriswamy, Arun Prasath
Nagaraj, Meena Gayathry
Rajaram Mohan, Karthik
Narayanan, Mohan
Karunakaran, Priyadeepalakshmi
Oral Manifestations of Type II Diabetes Mellitus and Comparison of Blood and Salivary Glucose Levels
title Oral Manifestations of Type II Diabetes Mellitus and Comparison of Blood and Salivary Glucose Levels
title_full Oral Manifestations of Type II Diabetes Mellitus and Comparison of Blood and Salivary Glucose Levels
title_fullStr Oral Manifestations of Type II Diabetes Mellitus and Comparison of Blood and Salivary Glucose Levels
title_full_unstemmed Oral Manifestations of Type II Diabetes Mellitus and Comparison of Blood and Salivary Glucose Levels
title_short Oral Manifestations of Type II Diabetes Mellitus and Comparison of Blood and Salivary Glucose Levels
title_sort oral manifestations of type ii diabetes mellitus and comparison of blood and salivary glucose levels
topic Dentistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445001/
https://www.ncbi.nlm.nih.gov/pubmed/37621821
http://dx.doi.org/10.7759/cureus.42344
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