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Detection and quantification of integrated vector copy number by multiplex droplet digital PCR in dual-transduced CAR T cells

The success of chimeric antigen receptor (CAR) T cell therapies in refractory hematologic malignancies has prompted investigation of their efficacy in solid tumors. AUTO6NG is a dual-transduced GD2-targeting CAR that encodes distinct modules designed to enhance T cell activity in relapsed/refractory...

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Detalles Bibliográficos
Autores principales:	Wang, Wei, Al-Hajj, Muhammad, Alavi, Alireza S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445099/ https://www.ncbi.nlm.nih.gov/pubmed/37622159 http://dx.doi.org/10.1016/j.omtm.2023.07.003

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