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Adult-type granulosa cell tumor of the testis: A case report and review of the literature

Granulosa cell tumors (GCTs) of the testicle are a rare subtype of sex cord stromal tumors which usually present with painless testicular swelling. The histology of an adult testicular GCT often resembles normal granulosa cell tissue morphology, with similar immunohistochemical staining pattern such...

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Detalles Bibliográficos
Autores principales: Satariano, Matthew, Losinski, Emily, Lane, Jason, Wegryn, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445446/
https://www.ncbi.nlm.nih.gov/pubmed/37621390
http://dx.doi.org/10.1016/j.eucr.2023.102532
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author Satariano, Matthew
Losinski, Emily
Lane, Jason
Wegryn, John
author_facet Satariano, Matthew
Losinski, Emily
Lane, Jason
Wegryn, John
author_sort Satariano, Matthew
collection PubMed
description Granulosa cell tumors (GCTs) of the testicle are a rare subtype of sex cord stromal tumors which usually present with painless testicular swelling. The histology of an adult testicular GCT often resembles normal granulosa cell tissue morphology, with similar immunohistochemical staining pattern such as positivity for steroidogenic factor 1 (SF1), calretinin, and inhibin A.(4,5) We present a case of a 39-year-old male with an adult GCT of the testicle who underwent successful unilateral orchiectomy. This case adds to the body of literature and furthers our understanding of tumor histopathology, tumor behavior, clinical surveillance, and treatment strategies for this testicular neoplasm.
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spelling pubmed-104454462023-08-24 Adult-type granulosa cell tumor of the testis: A case report and review of the literature Satariano, Matthew Losinski, Emily Lane, Jason Wegryn, John Urol Case Rep Oncology Granulosa cell tumors (GCTs) of the testicle are a rare subtype of sex cord stromal tumors which usually present with painless testicular swelling. The histology of an adult testicular GCT often resembles normal granulosa cell tissue morphology, with similar immunohistochemical staining pattern such as positivity for steroidogenic factor 1 (SF1), calretinin, and inhibin A.(4,5) We present a case of a 39-year-old male with an adult GCT of the testicle who underwent successful unilateral orchiectomy. This case adds to the body of literature and furthers our understanding of tumor histopathology, tumor behavior, clinical surveillance, and treatment strategies for this testicular neoplasm. Elsevier 2023-08-16 /pmc/articles/PMC10445446/ /pubmed/37621390 http://dx.doi.org/10.1016/j.eucr.2023.102532 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Oncology
Satariano, Matthew
Losinski, Emily
Lane, Jason
Wegryn, John
Adult-type granulosa cell tumor of the testis: A case report and review of the literature
title Adult-type granulosa cell tumor of the testis: A case report and review of the literature
title_full Adult-type granulosa cell tumor of the testis: A case report and review of the literature
title_fullStr Adult-type granulosa cell tumor of the testis: A case report and review of the literature
title_full_unstemmed Adult-type granulosa cell tumor of the testis: A case report and review of the literature
title_short Adult-type granulosa cell tumor of the testis: A case report and review of the literature
title_sort adult-type granulosa cell tumor of the testis: a case report and review of the literature
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445446/
https://www.ncbi.nlm.nih.gov/pubmed/37621390
http://dx.doi.org/10.1016/j.eucr.2023.102532
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