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Adult-type granulosa cell tumor of the testis: A case report and review of the literature
Granulosa cell tumors (GCTs) of the testicle are a rare subtype of sex cord stromal tumors which usually present with painless testicular swelling. The histology of an adult testicular GCT often resembles normal granulosa cell tissue morphology, with similar immunohistochemical staining pattern such...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445446/ https://www.ncbi.nlm.nih.gov/pubmed/37621390 http://dx.doi.org/10.1016/j.eucr.2023.102532 |
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author | Satariano, Matthew Losinski, Emily Lane, Jason Wegryn, John |
author_facet | Satariano, Matthew Losinski, Emily Lane, Jason Wegryn, John |
author_sort | Satariano, Matthew |
collection | PubMed |
description | Granulosa cell tumors (GCTs) of the testicle are a rare subtype of sex cord stromal tumors which usually present with painless testicular swelling. The histology of an adult testicular GCT often resembles normal granulosa cell tissue morphology, with similar immunohistochemical staining pattern such as positivity for steroidogenic factor 1 (SF1), calretinin, and inhibin A.(4,5) We present a case of a 39-year-old male with an adult GCT of the testicle who underwent successful unilateral orchiectomy. This case adds to the body of literature and furthers our understanding of tumor histopathology, tumor behavior, clinical surveillance, and treatment strategies for this testicular neoplasm. |
format | Online Article Text |
id | pubmed-10445446 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-104454462023-08-24 Adult-type granulosa cell tumor of the testis: A case report and review of the literature Satariano, Matthew Losinski, Emily Lane, Jason Wegryn, John Urol Case Rep Oncology Granulosa cell tumors (GCTs) of the testicle are a rare subtype of sex cord stromal tumors which usually present with painless testicular swelling. The histology of an adult testicular GCT often resembles normal granulosa cell tissue morphology, with similar immunohistochemical staining pattern such as positivity for steroidogenic factor 1 (SF1), calretinin, and inhibin A.(4,5) We present a case of a 39-year-old male with an adult GCT of the testicle who underwent successful unilateral orchiectomy. This case adds to the body of literature and furthers our understanding of tumor histopathology, tumor behavior, clinical surveillance, and treatment strategies for this testicular neoplasm. Elsevier 2023-08-16 /pmc/articles/PMC10445446/ /pubmed/37621390 http://dx.doi.org/10.1016/j.eucr.2023.102532 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Oncology Satariano, Matthew Losinski, Emily Lane, Jason Wegryn, John Adult-type granulosa cell tumor of the testis: A case report and review of the literature |
title | Adult-type granulosa cell tumor of the testis: A case report and review of the literature |
title_full | Adult-type granulosa cell tumor of the testis: A case report and review of the literature |
title_fullStr | Adult-type granulosa cell tumor of the testis: A case report and review of the literature |
title_full_unstemmed | Adult-type granulosa cell tumor of the testis: A case report and review of the literature |
title_short | Adult-type granulosa cell tumor of the testis: A case report and review of the literature |
title_sort | adult-type granulosa cell tumor of the testis: a case report and review of the literature |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445446/ https://www.ncbi.nlm.nih.gov/pubmed/37621390 http://dx.doi.org/10.1016/j.eucr.2023.102532 |
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