Dissection of tumor-intrinsic and tumor-extrinsic features of MiT/TFE translocation renal cell carcinoma via single-cell RNA sequencing

BACKGROUND: Translocation renal cell carcinoma (tRCC) is a rare and aggressive subtype of renal cell carcinoma driven by oncogenic gene fusions involving MiT/TFE family transcription factors, most commonly TFE3. Currently, there are no molecularly tailored treatments for tRCC, and standard-of-care t...

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Detalles Bibliográficos
Autores principales: Konda, Prathyusha, Einstein, David J, Zhang, Cheng-Zhong, Choueiri, Toni, Viswanathan, Srinivas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Rapid Abstract Presentations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445558/
http://dx.doi.org/10.1093/oncolo/oyad216.009

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