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Functional and translational consequences of immunometabolic coevolution in ccRCC
BACKGROUND: Tumor cell phenotypes and anti-tumor immune responses are shaped by local metabolite availability, but intratumoral metabolite heterogeneity (IMH) and its phenotypic consequences remain poorly understood. In vitro mechanistic studies have demonstrated that the anti-tumor activity of lymp...
Autores principales: | Reznik, Ed, Tang, Cerise, Xie, Amy, Minwei Liu, Eric, Kuo, Fengshen, Kim, Minsoo, Golkaram, Mahdi, Chen, Yingbei, Gupta, Sounak, Motzer, Robert, Russo, Paul, Coleman, Jonathan, Carloa, Maria, Voss, Martin, Kotecha, Ritesh, Han Lee, Chung, Tansey, Wesley, Schultz, Nikolaus, Ari Hakimi, A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445584/ http://dx.doi.org/10.1093/oncolo/oyad216.003 |
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