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PTK7 is a positive allosteric modulator of GPR133 signaling in glioblastoma

The adhesion G-protein-coupled receptor GPR133 (ADGRD1) supports growth of the brain malignancy glioblastoma. How the extracellular interactome of GPR133 in glioblastoma modulates signaling remains unknown. Here, we use affinity proteomics to identify the transmembrane protein PTK7 as an extracellul...

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Detalles Bibliográficos
Autores principales:	Frenster, Joshua D., Erdjument-Bromage, Hediye, Stephan, Gabriele, Ravn-Boess, Niklas, Wang, Shuai, Liu, Wenke, Bready, Devin, Wilcox, Jordan, Kieslich, Björn, Jankovic, Manuel, Wilde, Caroline, Horn, Susanne, Sträter, Norbert, Liebscher, Ines, Schöneberg, Torsten, Fenyo, David, Neubert, Thomas A., Placantonakis, Dimitris G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445595/ https://www.ncbi.nlm.nih.gov/pubmed/37354459 http://dx.doi.org/10.1016/j.celrep.2023.112679

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