Natural history of retinitis pigmentosa based on genotype, vitamin A/E supplementation, and an electroretinogram biomarker

BACKGROUND: A randomized clinical trial from 1984 to 1992 indicated that vitamin A supplementation had a beneficial effect on the progression of retinitis pigmentosa (RP), while vitamin E had an adverse effect. METHODS: Sequencing of banked DNA samples from that trial provided the opportunity to det...

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Detalles Bibliográficos
Autores principales: Comander, Jason, Weigel DiFranco, Carol, Sanderson, Kit, Place, Emily, Maher, Matthew, Zampaglione, Erin, Zhao, Yan, Huckfeldt, Rachel M., Bujakowska, Kinga M., Pierce, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445682/
https://www.ncbi.nlm.nih.gov/pubmed/37261916
http://dx.doi.org/10.1172/jci.insight.167546

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