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SRF deletion results in earlier disease onset in a mouse model of amyotrophic lateral sclerosis

Changes in neuronal activity modulate the vulnerability of motoneurons (MNs) in neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). So far, the molecular basis of neuronal activity’s impact in ALS is poorly understood. Herein, we investigated the impact of deleting the neurona...

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Detalles Bibliográficos
Autores principales:	Song, Jialei, Dikwella, Natalie, Sinske, Daniela, Roselli, Francesco, Knöll, Bernd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445689/ https://www.ncbi.nlm.nih.gov/pubmed/37339001 http://dx.doi.org/10.1172/jci.insight.167694

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