Cargando…

The rs17782313 polymorphism near MC4R gene confers a high risk of obesity and hyperglycemia, while PGC1α rs8192678 polymorphism is weakly correlated with glucometabolic disorder: a systematic review and meta-analysis

BACKGROUND: The relationships of the rs17782313 polymorphism near melanocortin 4 receptor gene (MC4R) and the rs8192678 polymorphism in peroxisome proliferator-activated receptor gamma coactivator 1 alpha gene (PGC1α) with metabolic abnormalities have been explored in many populations around the wor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Youjin, Li, Shiyun, Nie, Haiyan, Wang, Xue, Li, Xuanxuan, Wen, Jinhui, Li, Mengxi, Song, Yongyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445758/ https://www.ncbi.nlm.nih.gov/pubmed/37621650 http://dx.doi.org/10.3389/fendo.2023.1210455

Ejemplares similares

Evaluation of MC4R [RS17782313, RS17700633], AGRP [RS3412352] and POMC [RS1042571] polymorphisms with obesity in Northern India
por: Srivastava, Apurva, et al.
Publicado: (2014)

Systematic Meta-analysis Revealed an Association of PGC-1α rs8192678 Polymorphism in Type 2 Diabetes Mellitus
por: Xia, Wanning, et al.
Publicado: (2019)

Association of the rs17782313, rs17773430 and rs34114122 Polymorphisms of/near MC4R Gene with Obesity-Related Biomarkers in a Spanish Pediatric Cohort
por: Carrasco-Luna, Joaquín, et al.
Publicado: (2023)

Genetic association of the rs17782313 polymorphism with antipsychotic-induced weight gain
por: Schreyer, Korbinian Felix, et al.
Publicado: (2023)

The Obesity-Associated Polymorphisms FTO rs9939609 and MC4R rs17782313 and Endometrial Cancer Risk in Non-Hispanic White Women
por: Lurie, Galina, et al.
Publicado: (2011)

PPARGC1A rs8192678 and NRF1 rs6949152 Polymorphisms Are Associated with Muscle Fiber Composition in Women
por: Yvert, Thomas, et al.
Publicado: (2020)

Effects of the polymorphisms rs17782313 in mc4r gene and rs2282679 in VDBP gene on the TG-HDL ratio and HOMA-IR through pregnancy
por: Bagnasco, Nelly Janet Trujillo, et al.
Publicado: (2015)

Evaluation of FTO rs9939609 and MC4R rs17782313 Polymorphisms as Prognostic Biomarkers of Obesity: A Population-based Cross-sectional Study
por: Mozafarizadeh, Mina, et al.
Publicado: (2019)

Association of the PGC-1α rs8192678 Variant with Microalbuminuria in Subjects with Type 2 Diabetes Mellitus
por: Prior, Sarah L., et al.
Publicado: (2012)

Searching for the relationship between the parameters of metabolic syndrome and the rs17782313 (T>C) polymorphism of the MC4R gene in postmenopausal women
por: Brodowski, Jacek, et al.
Publicado: (2017)

MC4R variant rs17782313 and manifestation of obese phenotype in Pakistani females
por: Rana, Sobia, et al.
Publicado: (2018)

Impact of the Polymorphism Near MC4R (rs17782313) on Obesity- and Metabolic-Related Traits in Women Participating in an Aerobic Training Program
por: Leońska-Duniec, Agata, et al.
Publicado: (2017)

Association of MC4R (rs17782313) with diabetes and cardiovascular disease in Korean men and women
por: Sull, Jae Woong, et al.
Publicado: (2020)

Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the Mediterranean diet pattern is low
por: Ortega-Azorín, Carolina, et al.
Publicado: (2012)

Correlation Between PPARGC1A Gene Rs8192678 G>A Polymorphism and Susceptibility To Type-2 Diabetes
por: Du, Fei, et al.
Publicado: (2019)

Relationships between FTO rs9939609, MC4R rs17782313, and PPARγ rs1801282 polymorphisms and the occurrence of selected metabolic and hormonal disorders in middle-aged and elderly men – a preliminary study
por: Rotter, Iwona, et al.
Publicado: (2016)

Combined effects of FTO rs9939609 and MC4R rs17782313 on elevated nocturnal blood pressure in the Chinese Han population
por: Sun, Yanlei, et al.
Publicado: (2016)

Influence of Peroxisome Proliferator-Activated Receptor (PPAR)-gamma Coactivator (PGC)-1 alpha gene rs8192678 polymorphism by gender on different health-related parameters in healthy young adults
por: Montes-de-Oca-García, Adrián, et al.
Publicado: (2022)

Effects of FTO RS9939906 and MC4R RS17782313 on obesity, type 2 diabetes mellitus and blood pressure in patients with hypertension
por: Marcadenti, Aline, et al.
Publicado: (2013)

MC4R variants rs12970134 and rs17782313 are associated with obese polycystic ovary syndrome patients in the Western region of Saudi Arabia
por: Batarfi, Asma A., et al.
Publicado: (2019)

Predisposition of the Common MC4R rs17782313 Female Carriers to Elevated Obesity and Interaction with Eating Habits
por: Chermon, Danyel, et al.
Publicado: (2023)

Association and interaction of the MC4R rs17782313 polymorphism with plasma ghrelin, GLP-1, cortisol, food intake and eating behaviors in overweight/obese Iranian adults
por: Rahati, Sara, et al.
Publicado: (2022)

Engineered allele substitution at PPARGC1A rs8192678 alters human white adipocyte differentiation, lipogenesis, and PGC-1α content and turnover
por: Huang, Mi, et al.
Publicado: (2023)

An Obesity Risk SNP (rs17782313) near the MC4R Gene Is Associated with Cerebrocortical Insulin Resistance in Humans
por: Tschritter, Otto, et al.
Publicado: (2011)

Association of PPARGC1A Gly428Ser (rs8192678) polymorphism with potential for athletic ability and sports performance: A meta-analysis
por: Tharabenjasin, Phuntila, et al.
Publicado: (2019)

Dietary quality indices modifies the effects of melanocortin-4 receptor (MC4R) rs17782313 polymorphism on cardio-metabolic risk factors and hypothalamic hormones in obese adults
por: Khodarahmi, Mahdieh, et al.
Publicado: (2020)

Interactions with the MC4R rs17782313 variant, mental stress and energy intake and the risk of obesity in Genome Epidemiology Study
por: Park, Sunmin, et al.
Publicado: (2016)

Correction: Association of PPARGC1A Gly482Ser (rs8192678) polymorphism with potential for athletic ability and sports performance: A meta-analysis
por: Tharabenjasin, Phuntila, et al.
Publicado: (2021)

PPARGC1A rs8192678 G>A polymorphism affects the severity of hepatic histological features and nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease
por: Zhang, Rui-Nan, et al.
Publicado: (2021)

G Allele of the rs1801282 Polymorphism in PPARγ Gene Confers an Increased Risk of Obesity and Hypercholesterolemia, While T Allele of the rs3856806 Polymorphism Displays a Protective Role Against Dyslipidemia: A Systematic Review and Meta-Analysis
por: Li, Shujin, et al.
Publicado: (2022)

MeQTL analysis of childhood obesity links epigenetics with a risk SNP rs17782313 near MC4R from meta-analysis
por: Tang, Yuping, et al.
Publicado: (2016)

MC4R Variant rs17782313 Associates With Increased Levels of DNAJC27, Ghrelin, and Visfatin and Correlates With Obesity and Hypertension in a Kuwaiti Cohort
por: Hammad, Maha M., et al.
Publicado: (2020)

The Obesity Risk SNP (rs17782313) near the MC4R Gene Is Not Associated with Brain Glucose Uptake during Insulin Clamp—A Study in Finns
por: Rebelos, Eleni, et al.
Publicado: (2021)

The interaction between MC4R gene variant (rs17782313) and dominant dietary patterns on depression in obese and overweight women: a cross sectional study
por: Hajmir, Mahya Mehri, et al.
Publicado: (2023)

Associations of the APOB rs693 and rs17240441 polymorphisms with plasma APOB and lipid levels: a meta-analysis
por: Niu, Caiqin, et al.
Publicado: (2017)

Melanocortin-4 receptor (MC4R) rs17782313 polymorphism interacts with Dietary Approach to Stop Hypertension (DASH) and Mediterranean Dietary Score (MDS) to affect hypothalamic hormones and cardio-metabolic risk factors among obese individuals
por: Khodarahmi, Mahdieh, et al.
Publicado: (2020)

Predictive Value of Two Polymorphisms of ERCC2, rs13181 and rs1799793, in Clinical Outcomes of Chemotherapy in Gastric Cancer Patients: A Meta-Analysis
por: Li, Mengxi, et al.
Publicado: (2018)

Association of rs12487066, rs12044852, rs10735781, rs3135388, rs6897932, rs1321172, rs10492972, and rs9657904 Polymorphisms with Multiple Sclerosis in Iranian Population
por: Razavian, Takavar, et al.
Publicado: (2020)

Associations of the PON1 rs854560 polymorphism with plasma lipid levels: a meta-analysis
por: Luo, Zhi, et al.
Publicado: (2018)

Association of TFPI polymorphisms rs8176592, rs10931292, and rs10153820 with venous thrombosis: A meta-analysis
por: Zhang, Yunhong, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_j3b5v8u343kniklmgk24skj26v