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Direct oligonucleotide sequencing with nanopores
Third-generation DNA sequencing has enabled sequencing of long, unamplified DNA fragments with minimal steps. Direct sequencing of ssDNA or RNA gives valuable insights like base-level modifications, phosphoramidite synthesis yield estimates and strand quality analysis, without the need to add the co...
Autores principales: | Chalapati, Sachin, Crosbie, Conor A, Limbachiya, Dixita, Pinnamaneni, Nimesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445935/ https://www.ncbi.nlm.nih.gov/pubmed/37645114 http://dx.doi.org/10.12688/openreseurope.13578.2 |
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