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Application of In vitro transcytosis models to brain targeted biologics

The blood brain barrier (BBB) efficiently limits the penetration of biologics drugs from blood to brain. Establishment of an in vitro BBB model can facilitate screening of central nervous system (CNS) drug candidates and accelerate CNS drug development. Despite many established in vitro models, thei...

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Detalles Bibliográficos
Autores principales:	Deng, Kangwen, Lu, Yifeng, Finnema, Sjoerd J., Vangjeli, Kostika, Huang, Junwei, Huang, Lili, Goodearl, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10446226/ https://www.ncbi.nlm.nih.gov/pubmed/37611031 http://dx.doi.org/10.1371/journal.pone.0289970

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