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Differences in vestibulo‐ocular reflexes between vestibular neuritis and labyrinthitis

OBJECTIVE: To expand our understanding of the pathophysiological mechanisms underlying vestibular neuritis and labyrinthitis by identifying any difference in the vestibulo‐ocular reflex for each semicircular canal. STUDY DESIGN: Retrospective analysis. SETTING: The Department of Otorhinolaryngology...

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Autores principales: Nam, Gi‐Sung, Baek, Wonyong, Kim, Min Seok, Cho, Sung Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10446249/
https://www.ncbi.nlm.nih.gov/pubmed/37621282
http://dx.doi.org/10.1002/lio2.1092
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author Nam, Gi‐Sung
Baek, Wonyong
Kim, Min Seok
Cho, Sung Il
author_facet Nam, Gi‐Sung
Baek, Wonyong
Kim, Min Seok
Cho, Sung Il
author_sort Nam, Gi‐Sung
collection PubMed
description OBJECTIVE: To expand our understanding of the pathophysiological mechanisms underlying vestibular neuritis and labyrinthitis by identifying any difference in the vestibulo‐ocular reflex for each semicircular canal. STUDY DESIGN: Retrospective analysis. SETTING: The Department of Otorhinolaryngology – Head and Neck Surgery, Chosun University Hospital, from January 2015 to December 2021. METHODS: We included 23 vestibular neuritis and 27 labyrinthitis patients who had been hospitalized. Pure‐tone audiometry, a bithermal caloric test, and a video head‐impulse test were performed within 5 days of symptom onset. RESULTS: In the vestibular neuritis group, mean vestibulo‐ocular reflex gains were decreased to 0.51 in the ipsilesional horizontal canal and 0.55 in anterior canal, leading to marked asymmetry, whereas the gain of the ipsilesional posterior canal was relatively preserved at 0.85. In the labyrinthitis group, the mean vestibulo‐ocular reflex gain was 0.72 in the ipsilesional horizontal canal, 0.73 in the ipsilesional anterior canal, and 0.55 in the ipsilesional posterior canal. We observed statistical differences in the vestibulo‐ocular reflex gain and incidence of corrective saccades on the ipsilesional side in three semicircular canals between the groups (p = .002 for horizontal canal, p = .003 for anterior canal, and p < .001 for posterior canal). The receiver operating characteristic curve showed that pure‐tone audiometry, ipsilesional posterior canal gain, and gain asymmetry of posterior canal were excellent parameters for distinguishing labyrinthitis from vestibular neuritis. CONCLUSION: Vestibular neuritis and labyrinthitis patients have different degrees and patterns of video head‐impulse test involvement in the three semicircular canals, suggesting that the two distinct disorders may have different etiologies.
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spelling pubmed-104462492023-08-24 Differences in vestibulo‐ocular reflexes between vestibular neuritis and labyrinthitis Nam, Gi‐Sung Baek, Wonyong Kim, Min Seok Cho, Sung Il Laryngoscope Investig Otolaryngol Otology, Neurotology, and Neuroscience OBJECTIVE: To expand our understanding of the pathophysiological mechanisms underlying vestibular neuritis and labyrinthitis by identifying any difference in the vestibulo‐ocular reflex for each semicircular canal. STUDY DESIGN: Retrospective analysis. SETTING: The Department of Otorhinolaryngology – Head and Neck Surgery, Chosun University Hospital, from January 2015 to December 2021. METHODS: We included 23 vestibular neuritis and 27 labyrinthitis patients who had been hospitalized. Pure‐tone audiometry, a bithermal caloric test, and a video head‐impulse test were performed within 5 days of symptom onset. RESULTS: In the vestibular neuritis group, mean vestibulo‐ocular reflex gains were decreased to 0.51 in the ipsilesional horizontal canal and 0.55 in anterior canal, leading to marked asymmetry, whereas the gain of the ipsilesional posterior canal was relatively preserved at 0.85. In the labyrinthitis group, the mean vestibulo‐ocular reflex gain was 0.72 in the ipsilesional horizontal canal, 0.73 in the ipsilesional anterior canal, and 0.55 in the ipsilesional posterior canal. We observed statistical differences in the vestibulo‐ocular reflex gain and incidence of corrective saccades on the ipsilesional side in three semicircular canals between the groups (p = .002 for horizontal canal, p = .003 for anterior canal, and p < .001 for posterior canal). The receiver operating characteristic curve showed that pure‐tone audiometry, ipsilesional posterior canal gain, and gain asymmetry of posterior canal were excellent parameters for distinguishing labyrinthitis from vestibular neuritis. CONCLUSION: Vestibular neuritis and labyrinthitis patients have different degrees and patterns of video head‐impulse test involvement in the three semicircular canals, suggesting that the two distinct disorders may have different etiologies. John Wiley & Sons, Inc. 2023-06-13 /pmc/articles/PMC10446249/ /pubmed/37621282 http://dx.doi.org/10.1002/lio2.1092 Text en © 2023 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley Periodicals LLC on behalf of The Triological Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Otology, Neurotology, and Neuroscience
Nam, Gi‐Sung
Baek, Wonyong
Kim, Min Seok
Cho, Sung Il
Differences in vestibulo‐ocular reflexes between vestibular neuritis and labyrinthitis
title Differences in vestibulo‐ocular reflexes between vestibular neuritis and labyrinthitis
title_full Differences in vestibulo‐ocular reflexes between vestibular neuritis and labyrinthitis
title_fullStr Differences in vestibulo‐ocular reflexes between vestibular neuritis and labyrinthitis
title_full_unstemmed Differences in vestibulo‐ocular reflexes between vestibular neuritis and labyrinthitis
title_short Differences in vestibulo‐ocular reflexes between vestibular neuritis and labyrinthitis
title_sort differences in vestibulo‐ocular reflexes between vestibular neuritis and labyrinthitis
topic Otology, Neurotology, and Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10446249/
https://www.ncbi.nlm.nih.gov/pubmed/37621282
http://dx.doi.org/10.1002/lio2.1092
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