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Reduced thalamic excitation to motor cortical pyramidal tract neurons in parkinsonism

Degeneration of midbrain dopaminergic (DA) neurons alters the connectivity and functionality of the basal ganglia-thalamocortical circuits in Parkinson’s disease (PD). Particularly, the aberrant outputs of the primary motor cortex (M1) contribute to parkinsonian motor deficits. However, cortical ada...

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Detalles Bibliográficos
Autores principales:	Chen, Liqiang, Daniels, Samuel, Dvorak, Rachel, Chu, Hong-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10446482/ https://www.ncbi.nlm.nih.gov/pubmed/37611096 http://dx.doi.org/10.1126/sciadv.adg3038

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