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Nitrogen-15 dynamic nuclear polarization of nicotinamide derivatives in biocompatible solutions

Dissolution dynamic nuclear polarization (dDNP) increases the sensitivity of magnetic resonance imaging by more than 10,000 times, enabling in vivo metabolic imaging to be performed noninvasively in real time. Here, we are developing a group of dDNP polarized tracers based on nicotinamide (NAM). We...

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Detalles Bibliográficos
Autores principales: Peters, Josh P., Brahms, Arne, Janicaud, Vivian, Anikeeva, Maria, Peschke, Eva, Ellermann, Frowin, Ferrari, Arianna, Hellmold, Dana, Held-Feindt, Janka, Kim, Na-mi, Meiser, Johannes, Aden, Konrad, Herges, Rainer, Hövener, Jan-Bernd, Pravdivtsev, Andrey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10446501/
https://www.ncbi.nlm.nih.gov/pubmed/37611105
http://dx.doi.org/10.1126/sciadv.add3643

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