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Hypoxia-inducible factor 1 signaling drives placental aging and can provoke preterm labor

Most cases of preterm labor have unknown cause, and the burden of preterm birth is immense. Placental aging has been proposed to promote labor onset, but specific mechanisms remain elusive. We report findings stemming from unbiased transcriptomic analysis of mouse placenta, which revealed that hypox...

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Detalles Bibliográficos
Autores principales: Ciampa, Erin J, Flahardy, Padraich, Srinivasan, Harini, Jacobs, Christopher, Tsai, Linus, Karumanchi, S Ananth, Parikh, Samir M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10446824/
https://www.ncbi.nlm.nih.gov/pubmed/37610425
http://dx.doi.org/10.7554/eLife.85597