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Lessons in aging from Myc knockout mouse models

Despite MYC being among the most intensively studied oncogenes, its role in normal development has not been determined as Myc−/− mice do not survival beyond mid-gestation. Myc ± mice live longer than their wild-type counterparts and are slower to accumulate many age-related phenotypes. However, Myc...

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Detalles Bibliográficos
Autores principales: Prochownik, Edward V., Wang, Huabo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10446843/
https://www.ncbi.nlm.nih.gov/pubmed/37621775
http://dx.doi.org/10.3389/fcell.2023.1244321