A LGR5 reporter pig model closely resembles human intestine for improved study of stem cells in disease

Intestinal epithelial stem cells (ISCs) are responsible for intestinal epithelial barrier renewal; thereby, ISCs play a critical role in intestinal pathophysiology research. While transgenic ISC reporter mice are available, advanced translational studies lack a large animal model. This study validat...

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Detalles Bibliográficos
Autores principales: Schaaf, Cecilia R., Polkoff, Kathryn M., Carter, Amber, Stewart, Amy S., Sheahan, Breanna, Freund, John, Ginzel, Joshua, Snyder, Joshua C., Roper, Jatin, Piedrahita, Jorge A., Gonzalez, Liara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10446885/
https://www.ncbi.nlm.nih.gov/pubmed/37159340
http://dx.doi.org/10.1096/fj.202300223R

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