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Mesenchymal Stem Cell-Derived Exosomal miRNA-222-3p Increases Th1/Th2 Ratio and Promotes Apoptosis of Acute Myeloid Leukemia Cells

Interferon regulatory factor 2 (IRF2) participates in the differentiation of immune T cells. Bone marrow mesenchymal stem cell (BM-MSC)-derived exosomes can secret mRNA, miRNAs, and proteins to regulate tumor microenvironment. The present study focused on the miRNA/IRF2 axis in regulating Th1/Th2 ra...

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Detalles Bibliográficos
Autores principales: Yuan, Yuan, Tan, Shengfen, Wang, Huanhuan, Zhu, Junfeng, Li, Jiajia, Zhang, Pingping, Wang, Meng, Zhang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447000/
https://www.ncbi.nlm.nih.gov/pubmed/37621743
http://dx.doi.org/10.1155/2023/4024887

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