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Optimisation of Pharmaceutical Cocrystal Dissolution Performance through a Synergistic Precipitation Inhibition

OBJECTIVES: Polymeric excipients play an important role in a cocrystal formulation to act as precipitation inhibitors to maximize the potential. Otherwise, a stable form of the parent drug will be recrystallized on the dissolving cocrystal surface and/or in the bulk solution during the cocrystal dis...

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Detalles Bibliográficos
Autores principales: Shi, Kejing, Li, Mingzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447287/
https://www.ncbi.nlm.nih.gov/pubmed/37188904
http://dx.doi.org/10.1007/s11095-023-03532-x