Serum neurofilament light chain levels at attack predict post-attack disability worsening and are mitigated by inebilizumab: analysis of four potential biomarkers in neuromyelitis optica spectrum disorder

OBJECTIVE: To investigate relationships between serum neurofilament light chain (sNfL), ubiquitin C-terminal hydrolase L1 (sUCHL1), tau (sTau) and glial fibrillary acidic protein (sGFAP) levels and disease activity/disability in neuromyelitis optica spectrum disorder (NMOSD), and the effects of ineb...

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Detalles Bibliográficos
Autores principales: Aktas, Orhan, Hartung, Hans-Peter, Smith, Michael A, Rees, William A, Fujihara, Kazuo, Paul, Friedemann, Marignier, Romain, Bennett, Jeffrey L, Kim, Ho Jin, Weinshenker, Brian G, Pittock, Sean J, Wingerchuk, Dean M, Cutter, Gary, She, Dewei, Gunsior, Michele, Cimbora, Daniel, Katz, Eliezer, Cree, Bruce A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
General Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447388/
https://www.ncbi.nlm.nih.gov/pubmed/37221052
http://dx.doi.org/10.1136/jnnp-2022-330412

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